Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3746465..3747303 Replicon chromosome
Accession NZ_CP098731
Organism Stutzerimonas stutzeri strain NRCB010

Toxin (Protein)


Gene name yhaV Uniprot ID A4VQ36
Locus tag NDR94_RS17600 Protein ID WP_011914487.1
Coordinates 3746465..3746977 (-) Length 171 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A4VQ37
Locus tag NDR94_RS17605 Protein ID WP_011914488.1
Coordinates 3746974..3747303 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDR94_RS17580 (NDR94_17550) 3741486..3742133 + 648 WP_011914482.1 hypothetical protein -
NDR94_RS17585 (NDR94_17555) 3742216..3744396 + 2181 WP_011914483.1 ATP-binding protein -
NDR94_RS17590 (NDR94_17560) 3744468..3744839 + 372 WP_011914484.1 hypothetical protein -
NDR94_RS17595 (NDR94_17565) 3744894..3745901 + 1008 WP_041755950.1 WYL domain-containing protein -
NDR94_RS17600 (NDR94_17570) 3746465..3746977 - 513 WP_011914487.1 type II toxin-antitoxin system YhaV family toxin Toxin
NDR94_RS17605 (NDR94_17575) 3746974..3747303 - 330 WP_011914488.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
NDR94_RS17610 (NDR94_17580) 3747630..3749849 - 2220 WP_011914489.1 DEAD/DEAH box helicase -
NDR94_RS17615 (NDR94_17585) 3749824..3751119 - 1296 WP_014597639.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3740586..3761314 20728


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 19740.44 Da        Isoelectric Point: 9.7787

>T247934 WP_011914487.1 NZ_CP098731:c3746977-3746465 [Stutzerimonas stutzeri]
MSAGKPEPLVIHGWTVFAHPLFLAQIEVLARQVETLKQKDSVGYVKKNASKRLAAIIKLAFDVIPQDPTRPEYRQGGTLG
DDHKHWFRAKFFQQYRLFFRYHAPSKVIVFAWVNDDDTKRAYQSSDDAYRVFRKMLESGHPPDDWDRLLAEAQTESRRME
ESFARAATVQ

Download         Length: 513 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12056.53 Da        Isoelectric Point: 4.5642

>AT247934 WP_011914488.1 NZ_CP098731:c3747303-3746974 [Stutzerimonas stutzeri]
MAANFEVESTLTDRYQTTVPETVRRALKLGKRDKIHYTIRPSGEVVLTRVEASGSDDPVLGQFLSFLAADITRHPERLKS
VDTGLVQRLQSLVGDVDVDLDTVLSADDE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A4VQ36

Antitoxin

Source ID Structure
AlphaFold DB A4VQ37

References