Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2644515..2644777 Replicon chromosome
Accession NZ_CP098727
Organism Staphylococcus aureus strain SauR3

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LC189_RS12865 Protein ID WP_001802298.1
Coordinates 2644515..2644619 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2644614..2644777 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LC189_RS12850 (LC189_012850) 2641312..2642094 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
LC189_RS12855 (LC189_012855) 2642162..2643019 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
LC189_RS12860 (LC189_012860) 2643677..2643835 - 159 WP_001792784.1 hypothetical protein -
LC189_RS12865 (LC189_012865) 2644515..2644619 + 105 WP_001802298.1 hypothetical protein Toxin
- 2644614..2644777 - 164 - - Antitoxin
LC189_RS12875 (LC189_012875) 2645127..2646218 - 1092 WP_000495682.1 hypothetical protein -
LC189_RS12880 (LC189_012880) 2646484..2647464 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
LC189_RS12885 (LC189_012885) 2647466..2647786 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LC189_RS12890 (LC189_012890) 2647938..2648603 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T247929 WP_001802298.1 NZ_CP098727:2644515-2644619 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT247929 NZ_CP098727:c2644777-2644614 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References