Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2361687..2361871 Replicon chromosome
Accession NZ_CP098727
Organism Staphylococcus aureus strain SauR3

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LC189_RS11390 Protein ID WP_000482647.1
Coordinates 2361687..2361794 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2361811..2361871 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LC189_RS11365 (LC189_011365) 2357059..2357532 + 474 WP_000456486.1 GyrI-like domain-containing protein -
LC189_RS11370 (LC189_011370) 2357655..2358866 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
LC189_RS11375 (LC189_011375) 2359048..2359707 - 660 WP_000831301.1 membrane protein -
LC189_RS11380 (LC189_011380) 2359767..2360909 - 1143 WP_001176863.1 glycerate kinase -
LC189_RS11385 (LC189_011385) 2361167..2361553 + 387 WP_000779360.1 flippase GtxA -
LC189_RS11390 (LC189_011390) 2361687..2361794 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2361811..2361871 - 61 - - Antitoxin
LC189_RS11395 (LC189_011395) 2362501..2364264 + 1764 WP_001064814.1 ABC transporter ATP-binding protein -
LC189_RS11400 (LC189_011400) 2364289..2366022 + 1734 WP_000486506.1 ABC transporter ATP-binding protein -
LC189_RS11405 (LC189_011405) 2366289..2366420 + 132 WP_223223631.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T247927 WP_000482647.1 NZ_CP098727:2361687-2361794 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT247927 NZ_CP098727:c2361871-2361811 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References