Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 1216716..1217301 Replicon chromosome
Accession NC_014216
Organism Desulfurivibrio alkaliphilus AHT2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DAAHT2_RS05180 Protein ID WP_013163244.1
Coordinates 1216996..1217301 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DAAHT2_RS05175 Protein ID WP_013163243.1
Coordinates 1216716..1217003 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DAAHT2_RS05165 1212188..1212655 - 468 WP_157861420.1 hypothetical protein -
DAAHT2_RS14250 1212795..1214072 - 1278 WP_013163240.1 reverse transcriptase/maturase family protein -
DAAHT2_RS14620 1214480..1215187 - 708 WP_013163242.1 hypothetical protein -
DAAHT2_RS05170 1215678..1216289 - 612 Protein_1016 Fic family protein -
DAAHT2_RS05175 1216716..1217003 - 288 WP_013163243.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
DAAHT2_RS05180 1216996..1217301 - 306 WP_013163244.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DAAHT2_RS05185 1217483..1217755 - 273 WP_013163245.1 hypothetical protein -
DAAHT2_RS14855 1217815..1218042 + 228 WP_174259450.1 hypothetical protein -
DAAHT2_RS05195 1218112..1218339 + 228 WP_013163246.1 rubredoxin -
DAAHT2_RS14260 1218406..1218678 + 273 WP_013163247.1 hypothetical protein -
DAAHT2_RS05205 1218767..1219693 + 927 WP_013163248.1 patatin-like phospholipase family protein -
DAAHT2_RS05210 1219834..1220943 + 1110 WP_013163249.1 MipA/OmpV family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-95)

Antitoxin

Antitoxin MqsA/HigA-2

(34-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11371.04 Da        Isoelectric Point: 9.7632

>T24779 WP_013163244.1 NC_014216:c1217301-1216996 [Desulfurivibrio alkaliphilus AHT 2]
IYETSIFTKLLRNYLSDEEYCGLQTYLLQKPDAGDLIKGSGGVRKVRWASAGTGKSGGLRVIYYWKKSDHEIWMLTLYSK
SERASIPGHTLKQIAEAIKNG

Download         Length: 306 bp

>T24779 NC_014216:c1217301-1216996 [Desulfurivibrio alkaliphilus AHT 2]
ATTTATGAAACATCGATTTTTACCAAGCTGTTGCGCAACTACCTCTCGGACGAGGAATATTGTGGGCTGCAAACCTATCT
ATTGCAGAAGCCGGATGCTGGCGATCTCATCAAGGGATCAGGTGGTGTTCGCAAGGTTCGATGGGCGTCGGCGGGTACGG
GAAAGAGCGGTGGCCTCAGGGTGATTTATTACTGGAAAAAATCTGACCACGAGATATGGATGCTCACACTTTACAGTAAA
TCGGAGCGGGCCAGTATTCCCGGGCATACGCTCAAGCAGATAGCGGAGGCAATCAAAAATGGCTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10631.42 Da        Isoelectric Point: 10.6470

>AT24779 WP_013163243.1 NC_014216:c1217003-1216716 [Desulfurivibrio alkaliphilus AHT 2]
MADRNLGAEILDGINEIKRFKKGKLELRTHELSAPSPPKVIRLKLKMSQSAFAGLMGVSVRTLQDWEQGRREPQGPAVAL
LRIVEQHPEVLGQLH

Download         Length: 288 bp

>AT24779 NC_014216:c1217003-1216716 [Desulfurivibrio alkaliphilus AHT 2]
ATGGCTGACAGGAACCTTGGAGCAGAAATCCTTGACGGTATCAATGAGATTAAGCGGTTCAAGAAAGGCAAACTGGAACT
GCGGACCCATGAACTTTCAGCACCGTCTCCACCCAAGGTGATTCGGCTGAAATTAAAGATGTCGCAATCGGCTTTTGCCG
GTCTCATGGGAGTAAGCGTGCGGACCCTTCAGGACTGGGAGCAGGGGCGGCGGGAACCGCAAGGCCCGGCGGTTGCGCTC
TTGCGTATTGTAGAGCAACACCCGGAAGTGCTTGGCCAGCTTCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References