247756

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3177883..3178715 Replicon chromosome
Accession NZ_CP098611
Organism Phormidium yuhuli AB48

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag NEA10_RS13525 Protein ID WP_252661176.1
Coordinates 3177883..3178380 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag NEA10_RS13530 Protein ID WP_252661178.1
Coordinates 3178383..3178715 (-) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NEA10_RS13510 (NEA10_13510) 3172926..3174314 - 1389 WP_252661170.1 BamA/TamA family outer membrane protein -
NEA10_RS13515 (NEA10_13515) 3174463..3176472 - 2010 WP_252661172.1 ABC transporter ATP-binding protein -
NEA10_RS13520 (NEA10_13520) 3176576..3177706 - 1131 WP_252661174.1 peptidylprolyl isomerase -
NEA10_RS13525 (NEA10_13525) 3177883..3178380 - 498 WP_252661176.1 type II toxin-antitoxin system YhaV family toxin Toxin
NEA10_RS13530 (NEA10_13530) 3178383..3178715 - 333 WP_252661178.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
NEA10_RS13535 (NEA10_13535) 3178887..3180716 - 1830 WP_252661180.1 threonine--tRNA ligase -
NEA10_RS13540 (NEA10_13540) 3180919..3181311 + 393 WP_252661181.1 YggT family protein -
NEA10_RS13545 (NEA10_13545) 3181365..3182141 - 777 WP_252661183.1 LemA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(14-150)

Antitoxin

PrlF antitoxin

(10-108)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 19603.32 Da        Isoelectric Point: 9.5181

>T247756 WP_252661176.1 NZ_CP098611:c3178380-3177883 [Phormidium yuhuli AB48]
VSSEQPIIINGWTLFAHPLFLSQVETLVTQVERLRQKDAQGYKRKNVTKRLAAIARLAFEIIPEDPTRPNYRQGSTLGPE
YKHWFRAKFFQQYRLFFRYHQESKIIVLAWVNDETSKRAYDRDTDAYRVFAKMLDQGHPPDDWEALMQEVSQTTERLKKI
LDQEI

Download         Length: 498 bp

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12056.51 Da        Isoelectric Point: 3.9655

>AT247756 WP_252661178.1 NZ_CP098611:c3178715-3178383 [Phormidium yuhuli AB48]
MARPSQPCSESTLTARYQTTIPEPIRKFLGLAKGDKIQYSIEPDGQVLISVAKDSSDDPVLGAFLEFIEQDMSKNPQNLQ
PVPANLVNRVQSLVADVDVSLDEPLADEDE

Download         Length: 333 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References