Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1535102..1535568 Replicon chromosome
Accession NZ_CP098511
Organism Aquimarina sp. ERC-38

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NBT05_RS06585 Protein ID WP_265772698.1
Coordinates 1535314..1535568 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NBT05_RS06580 Protein ID WP_265772697.1
Coordinates 1535102..1535311 (+) Length 70 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBT05_RS06560 (NBT05_06550) 1530191..1530967 - 777 WP_265773216.1 DUF3108 domain-containing protein -
NBT05_RS06565 (NBT05_06555) 1531379..1532512 - 1134 WP_265772695.1 4-hydroxyphenylpyruvate dioxygenase -
NBT05_RS06570 (NBT05_06560) 1532804..1533961 - 1158 WP_265772696.1 homogentisate 1,2-dioxygenase -
NBT05_RS06575 (NBT05_06565) 1534252..1535019 - 768 WP_265770084.1 IS5 family transposase -
NBT05_RS06580 (NBT05_06570) 1535102..1535311 + 210 WP_265772697.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NBT05_RS06585 (NBT05_06575) 1535314..1535568 + 255 WP_265772698.1 Txe/YoeB family addiction module toxin Toxin
NBT05_RS06590 (NBT05_06580) 1535650..1537170 - 1521 WP_265772699.1 carboxypeptidase-like regulatory domain-containing protein -
NBT05_RS06595 (NBT05_06585) 1537582..1539849 - 2268 WP_265772700.1 patatin-like phospholipase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-83)

Antitoxin

(2-57)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 9897.40 Da        Isoelectric Point: 9.1764

>T247719 WP_265772698.1 NZ_CP098511:1535314-1535568 [Aquimarina sp. ERC-38]
MKLVWSTSSWEDYLYCQKTNKSTIKRINQLIKSALRTPFEGIGKPEALKGDLQGYWSRRITSEHRLVYKFEENSLFIASC
CYHC

Download         Length: 255 bp


Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7753.88 Da        Isoelectric Point: 4.5258

>AT247719 WP_265772697.1 NZ_CP098511:1535102-1535311 [Aquimarina sp. ERC-38]
MLLDKVVDDVSDIVIKRKGGKDLVLISLEEYNSLKETNYLLTGKNRDVLLDSIKELENGNGITKNISDF

Download         Length: 210 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References