Detailed information of TA system TA247610

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 19234..19448
• Replicon: plasmid pCQ025-3
• Accession: NZ_CP098421
• Organism: Enterococcus faecalis strain CQ025

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: NAG09_RS14865
• Protein ID: WP_002360667.1
• Coordinates: 19234..19344 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	19384..19448 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NAG09_RS14825	14315..14545	-	231	WP_002362431.1	hypothetical protein	-
NAG09_RS14830	14749..15369	+	621	WP_161971471.1	recombinase family protein	-
NAG09_RS14835	15386..15550	+	165	WP_250652966.1	hypothetical protein	-
NAG09_RS14845	16954..17187	+	234	WP_002394799.1	hypothetical protein	-
NAG09_RS14850	17347..17601	-	255	WP_002394800.1	hypothetical protein	-
NAG09_RS14855	17718..18386	-	669	WP_002403283.1	CPBP family intramembrane metalloprotease	-
NAG09_RS14860	18422..18739	-	318	WP_002394802.1	heavy metal-binding domain-containing protein	-
NAG09_RS14865	19234..19344	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	19384..19448	-	65	-	-	Antitoxin
NAG09_RS14870	19584..19883	+	300	WP_010817802.1	hypothetical protein	-
NAG09_RS14875	20668..21210	-	543	WP_086321354.1	hypothetical protein	-
NAG09_RS14880	21220..22071	-	852	WP_002362419.1	ParA family protein	-
NAG09_RS14885	22734..23750	+	1017	WP_033593833.1	replication initiator protein A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	dfrG / aph(3')-III / erm(B)	-	1..59669	59669

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T247610 WP_002360667.1 NZ_CP098421:19234-19344 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT247610 NZ_CP098421:c19448-19384 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin