Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2456084..2456742 Replicon chromosome
Accession NZ_CP098325
Organism Leclercia adecarboxylata strain kcgeb_e1

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag NB069_RS11760 Protein ID WP_250589502.1
Coordinates 2456488..2456742 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag NB069_RS11755 Protein ID WP_250583744.1
Coordinates 2456084..2456491 (-) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB069_RS11735 (NB069_11735) 2451687..2452169 - 483 WP_250583736.1 glutathione peroxidase -
NB069_RS11740 (NB069_11740) 2452229..2453692 - 1464 WP_250583738.1 DUF1254 domain-containing protein -
NB069_RS11745 (NB069_11745) 2453703..2455181 - 1479 WP_250583740.1 DUF1254 domain-containing protein -
NB069_RS11750 (NB069_11750) 2455377..2456054 + 678 WP_250583742.1 SOS response-associated peptidase -
NB069_RS11755 (NB069_11755) 2456084..2456491 - 408 WP_250583744.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NB069_RS11760 (NB069_11760) 2456488..2456742 - 255 WP_250589502.1 type II toxin-antitoxin system MqsR family toxin Toxin
NB069_RS11765 (NB069_11765) 2456872..2456970 + 99 Protein_2301 SOS response-associated peptidase -
NB069_RS11770 (NB069_11770) 2457403..2457552 - 150 Protein_2302 DUF4113 domain-containing protein -
NB069_RS11775 (NB069_11775) 2458134..2459399 + 1266 WP_250583746.1 Y-family DNA polymerase -
NB069_RS11780 (NB069_11780) 2459447..2460232 - 786 WP_250583748.1 IclR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2446108..2473552 27444


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(76-129)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9550.09 Da        Isoelectric Point: 6.9649

>T247412 WP_250589502.1 NZ_CP098325:c2456742-2456488 [Leclercia adecarboxylata]
MVRAGLTAVTHSALIGAARMGFCSRQEIFDVVLALEPTDFYKSMTAHHDHTCWHDVYRTVYKDQTIYMKLIVTDGVLVVS
FKEL

Download         Length: 255 bp

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 15025.27 Da        Isoelectric Point: 7.1892

>AT247412 WP_250583744.1 NZ_CP098325:c2456491-2456084 [Leclercia adecarboxylata]
MKMKCPVCGGAALKHESRDVAYEYKGQKTIFHAVKGQFCDACGEIIFANGEGDDYFAAMLEFNRKVNAEEVDPTFIAKVR
KRLNLDQRQAAEIFGGGVNAFSRYETGRVAPPKPLVLLFKALDKHPELLDELTQA

Download         Length: 408 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References