Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2137789..2138051 Replicon chromosome
Accession NZ_CP098257
Organism Staphylococcus aureus strain M4

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag NB631_RS10220 Protein ID WP_073392962.1
Coordinates 2137789..2137893 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2137888..2138051 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB631_RS10205 (NB631_10210) 2134585..2135367 + 783 WP_000908186.1 ABC transporter ATP-binding protein -
NB631_RS10210 (NB631_10215) 2135435..2136292 + 858 WP_000370937.1 HAD family hydrolase -
NB631_RS10215 (NB631_10220) 2136951..2137109 - 159 WP_001792784.1 hypothetical protein -
NB631_RS10220 (NB631_10225) 2137789..2137893 + 105 WP_073392962.1 hypothetical protein Toxin
- 2137888..2138051 - 164 - - Antitoxin
NB631_RS10230 (NB631_10235) 2138335..2139426 - 1092 WP_000495684.1 hypothetical protein -
NB631_RS10235 (NB631_10240) 2139692..2140672 - 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
NB631_RS10240 (NB631_10245) 2140674..2140994 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NB631_RS10245 (NB631_10250) 2141146..2141811 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T247391 WP_073392962.1 NZ_CP098257:2137789-2137893 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT247391 NZ_CP098257:c2138051-2137888 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References