Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1852707..1852891 Replicon chromosome
Accession NZ_CP098257
Organism Staphylococcus aureus strain M4

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NB631_RS08725 Protein ID WP_000482647.1
Coordinates 1852707..1852814 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1852831..1852891 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB631_RS08700 (NB631_08705) 1848069..1848542 + 474 WP_000456499.1 GyrI-like domain-containing protein -
NB631_RS08705 (NB631_08710) 1848665..1849876 - 1212 WP_001191919.1 multidrug effflux MFS transporter -
NB631_RS08710 (NB631_08715) 1850058..1850717 - 660 WP_000831298.1 membrane protein -
NB631_RS08715 (NB631_08720) 1850777..1851919 - 1143 WP_001176855.1 glycerate kinase -
NB631_RS08720 (NB631_08725) 1852187..1852573 + 387 WP_000779351.1 flippase GtxA -
NB631_RS08725 (NB631_08730) 1852707..1852814 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1852831..1852891 - 61 - - Antitoxin
NB631_RS08730 (NB631_08735) 1853462..1855225 + 1764 WP_001064828.1 ATP-binding cassette domain-containing protein -
NB631_RS08735 (NB631_08740) 1855250..1856983 + 1734 WP_000486507.1 ABC transporter ATP-binding protein -
NB631_RS08740 (NB631_08745) 1857214..1857381 + 168 Protein_1721 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T247389 WP_000482647.1 NZ_CP098257:1852707-1852814 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT247389 NZ_CP098257:c1852891-1852831 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References