Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 421467..422076 Replicon chromosome
Accession NZ_CP098247
Organism Oxalobacter aliiformigenes strain BA2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NB636_RS02010 Protein ID WP_269280948.1
Coordinates 421732..422076 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NB636_RS02005 Protein ID WP_269280950.1
Coordinates 421467..421751 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB636_RS01985 (NB636_01980) 416576..417064 + 489 WP_269280961.1 terminase small subunit -
NB636_RS01990 (NB636_01985) 417040..418428 + 1389 WP_269280958.1 terminase family protein -
NB636_RS01995 (NB636_01990) 418432..420345 + 1914 WP_269280956.1 hypothetical protein -
NB636_RS02000 (NB636_01995) 420354..421373 + 1020 WP_269280953.1 hypothetical protein -
NB636_RS02005 (NB636_02000) 421467..421751 - 285 WP_269280950.1 helix-turn-helix domain-containing protein Antitoxin
NB636_RS02010 (NB636_02005) 421732..422076 - 345 WP_269280948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NB636_RS02015 (NB636_02010) 422118..422375 + 258 WP_269280947.1 antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 406912..455607 48695


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13404.50 Da        Isoelectric Point: 10.4974

>T247353 WP_269280948.1 NZ_CP098247:c422076-421732 [Oxalobacter aliiformigenes]
MKKQYSIDYYNDDIRQDVDRWPVSLRARYARLTERMKIYGGNLGEPHTKAFGNGLFELRVKAEVGIGRAFFCTKVGRKII
ILHSFIKKTQKTPKHDLDIALSRMKEKRDEQDSR

Download         Length: 345 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10540.17 Da        Isoelectric Point: 8.5619

>AT247353 WP_269280950.1 NZ_CP098247:c421751-421467 [Oxalobacter aliiformigenes]
MSKTHDEMVSEWMKDPAFREEYDKLEAEFRLLDDILAARNAAGLTQAQVAERMGTTQSSVARLEKGLASGSLPSMSMLKR
YAQVVGKKLHVRLI

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References