Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-ohsC/Ldr(toxin)
Location 2141549..2141770 Replicon chromosome
Accession NZ_CP098223
Organism Escherichia coli strain Z0117EC0005

Toxin (Protein)


Gene name ldrD Uniprot ID L4JC91
Locus tag NBY12_RS10280 Protein ID WP_000170956.1
Coordinates 2141549..2141656 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name ohsC
Locus tag -
Coordinates 2141709..2141770 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY12_RS10250 (2136859) 2136859..2137941 + 1083 WP_000804726.1 peptide chain release factor 1 -
NBY12_RS10255 (2137941) 2137941..2138774 + 834 WP_032302913.1 peptide chain release factor N(5)-glutamine methyltransferase -
NBY12_RS10260 (2138771) 2138771..2139163 + 393 WP_000200378.1 invasion regulator SirB2 -
NBY12_RS10265 (2139167) 2139167..2139976 + 810 WP_032302914.1 invasion regulator SirB1 -
NBY12_RS10270 (2140012) 2140012..2140866 + 855 WP_032302915.1 3-deoxy-8-phosphooctulonate synthase -
NBY12_RS10275 (2141014) 2141014..2141121 - 108 WP_022645587.1 type I toxin-antitoxin system toxin Ldr family protein -
- (2141169) 2141169..2141234 + 66 NuclAT_11 - -
- (2141169) 2141169..2141234 + 66 NuclAT_11 - -
- (2141169) 2141169..2141234 + 66 NuclAT_11 - -
- (2141169) 2141169..2141234 + 66 NuclAT_11 - -
- (2141169) 2141169..2141234 + 66 NuclAT_13 - -
- (2141169) 2141169..2141234 + 66 NuclAT_13 - -
- (2141169) 2141169..2141234 + 66 NuclAT_13 - -
- (2141169) 2141169..2141234 + 66 NuclAT_13 - -
- (2141169) 2141169..2141234 + 66 NuclAT_15 - -
- (2141169) 2141169..2141234 + 66 NuclAT_15 - -
- (2141169) 2141169..2141234 + 66 NuclAT_15 - -
- (2141169) 2141169..2141234 + 66 NuclAT_15 - -
- (2141169) 2141169..2141234 + 66 NuclAT_17 - -
- (2141169) 2141169..2141234 + 66 NuclAT_17 - -
- (2141169) 2141169..2141234 + 66 NuclAT_17 - -
- (2141169) 2141169..2141234 + 66 NuclAT_17 - -
- (2141169) 2141169..2141234 + 66 NuclAT_7 - -
- (2141169) 2141169..2141234 + 66 NuclAT_7 - -
- (2141169) 2141169..2141234 + 66 NuclAT_7 - -
- (2141169) 2141169..2141234 + 66 NuclAT_7 - -
- (2141169) 2141169..2141234 + 66 NuclAT_9 - -
- (2141169) 2141169..2141234 + 66 NuclAT_9 - -
- (2141169) 2141169..2141234 + 66 NuclAT_9 - -
- (2141169) 2141169..2141234 + 66 NuclAT_9 - -
- (2141170) 2141170..2141235 + 66 NuclAT_21 - -
- (2141170) 2141170..2141235 + 66 NuclAT_21 - -
- (2141170) 2141170..2141235 + 66 NuclAT_21 - -
- (2141170) 2141170..2141235 + 66 NuclAT_21 - -
- (2141170) 2141170..2141235 + 66 NuclAT_25 - -
- (2141170) 2141170..2141235 + 66 NuclAT_25 - -
- (2141170) 2141170..2141235 + 66 NuclAT_25 - -
- (2141170) 2141170..2141235 + 66 NuclAT_25 - -
- (2141170) 2141170..2141235 + 66 NuclAT_29 - -
- (2141170) 2141170..2141235 + 66 NuclAT_29 - -
- (2141170) 2141170..2141235 + 66 NuclAT_29 - -
- (2141170) 2141170..2141235 + 66 NuclAT_29 - -
- (2141170) 2141170..2141235 + 66 NuclAT_33 - -
- (2141170) 2141170..2141235 + 66 NuclAT_33 - -
- (2141170) 2141170..2141235 + 66 NuclAT_33 - -
- (2141170) 2141170..2141235 + 66 NuclAT_33 - -
- (2141170) 2141170..2141235 + 66 NuclAT_37 - -
- (2141170) 2141170..2141235 + 66 NuclAT_37 - -
- (2141170) 2141170..2141235 + 66 NuclAT_37 - -
- (2141170) 2141170..2141235 + 66 NuclAT_37 - -
- (2141170) 2141170..2141235 + 66 NuclAT_41 - -
- (2141170) 2141170..2141235 + 66 NuclAT_41 - -
- (2141170) 2141170..2141235 + 66 NuclAT_41 - -
- (2141170) 2141170..2141235 + 66 NuclAT_41 - -
- (2141169) 2141169..2141236 + 68 NuclAT_19 - -
- (2141169) 2141169..2141236 + 68 NuclAT_19 - -
- (2141169) 2141169..2141236 + 68 NuclAT_19 - -
- (2141169) 2141169..2141236 + 68 NuclAT_19 - -
- (2141169) 2141169..2141236 + 68 NuclAT_23 - -
- (2141169) 2141169..2141236 + 68 NuclAT_23 - -
- (2141169) 2141169..2141236 + 68 NuclAT_23 - -
- (2141169) 2141169..2141236 + 68 NuclAT_23 - -
- (2141169) 2141169..2141236 + 68 NuclAT_27 - -
- (2141169) 2141169..2141236 + 68 NuclAT_27 - -
- (2141169) 2141169..2141236 + 68 NuclAT_27 - -
- (2141169) 2141169..2141236 + 68 NuclAT_27 - -
- (2141169) 2141169..2141236 + 68 NuclAT_31 - -
- (2141169) 2141169..2141236 + 68 NuclAT_31 - -
- (2141169) 2141169..2141236 + 68 NuclAT_31 - -
- (2141169) 2141169..2141236 + 68 NuclAT_31 - -
- (2141169) 2141169..2141236 + 68 NuclAT_35 - -
- (2141169) 2141169..2141236 + 68 NuclAT_35 - -
- (2141169) 2141169..2141236 + 68 NuclAT_35 - -
- (2141169) 2141169..2141236 + 68 NuclAT_35 - -
- (2141169) 2141169..2141236 + 68 NuclAT_39 - -
- (2141169) 2141169..2141236 + 68 NuclAT_39 - -
- (2141169) 2141169..2141236 + 68 NuclAT_39 - -
- (2141169) 2141169..2141236 + 68 NuclAT_39 - -
NBY12_RS10280 (2141549) 2141549..2141656 - 108 WP_000170956.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (2141709) 2141709..2141770 + 62 NuclAT_10 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_10 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_10 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_10 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_12 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_12 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_12 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_12 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_14 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_14 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_14 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_14 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_16 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_16 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_16 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_16 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_18 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_18 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_18 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_18 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_8 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_8 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_8 - Antitoxin
- (2141709) 2141709..2141770 + 62 NuclAT_8 - Antitoxin
- (2141709) 2141709..2141771 + 63 NuclAT_22 - -
- (2141709) 2141709..2141771 + 63 NuclAT_22 - -
- (2141709) 2141709..2141771 + 63 NuclAT_22 - -
- (2141709) 2141709..2141771 + 63 NuclAT_22 - -
- (2141709) 2141709..2141771 + 63 NuclAT_26 - -
- (2141709) 2141709..2141771 + 63 NuclAT_26 - -
- (2141709) 2141709..2141771 + 63 NuclAT_26 - -
- (2141709) 2141709..2141771 + 63 NuclAT_26 - -
- (2141709) 2141709..2141771 + 63 NuclAT_30 - -
- (2141709) 2141709..2141771 + 63 NuclAT_30 - -
- (2141709) 2141709..2141771 + 63 NuclAT_30 - -
- (2141709) 2141709..2141771 + 63 NuclAT_30 - -
- (2141709) 2141709..2141771 + 63 NuclAT_34 - -
- (2141709) 2141709..2141771 + 63 NuclAT_34 - -
- (2141709) 2141709..2141771 + 63 NuclAT_34 - -
- (2141709) 2141709..2141771 + 63 NuclAT_34 - -
- (2141709) 2141709..2141771 + 63 NuclAT_38 - -
- (2141709) 2141709..2141771 + 63 NuclAT_38 - -
- (2141709) 2141709..2141771 + 63 NuclAT_38 - -
- (2141709) 2141709..2141771 + 63 NuclAT_38 - -
- (2141709) 2141709..2141771 + 63 NuclAT_42 - -
- (2141709) 2141709..2141771 + 63 NuclAT_42 - -
- (2141709) 2141709..2141771 + 63 NuclAT_42 - -
- (2141709) 2141709..2141771 + 63 NuclAT_42 - -
- (2141709) 2141709..2141772 + 64 NuclAT_20 - -
- (2141709) 2141709..2141772 + 64 NuclAT_20 - -
- (2141709) 2141709..2141772 + 64 NuclAT_20 - -
- (2141709) 2141709..2141772 + 64 NuclAT_20 - -
- (2141709) 2141709..2141772 + 64 NuclAT_24 - -
- (2141709) 2141709..2141772 + 64 NuclAT_24 - -
- (2141709) 2141709..2141772 + 64 NuclAT_24 - -
- (2141709) 2141709..2141772 + 64 NuclAT_24 - -
- (2141709) 2141709..2141772 + 64 NuclAT_28 - -
- (2141709) 2141709..2141772 + 64 NuclAT_28 - -
- (2141709) 2141709..2141772 + 64 NuclAT_28 - -
- (2141709) 2141709..2141772 + 64 NuclAT_28 - -
- (2141709) 2141709..2141772 + 64 NuclAT_32 - -
- (2141709) 2141709..2141772 + 64 NuclAT_32 - -
- (2141709) 2141709..2141772 + 64 NuclAT_32 - -
- (2141709) 2141709..2141772 + 64 NuclAT_32 - -
- (2141709) 2141709..2141772 + 64 NuclAT_36 - -
- (2141709) 2141709..2141772 + 64 NuclAT_36 - -
- (2141709) 2141709..2141772 + 64 NuclAT_36 - -
- (2141709) 2141709..2141772 + 64 NuclAT_36 - -
- (2141709) 2141709..2141772 + 64 NuclAT_40 - -
- (2141709) 2141709..2141772 + 64 NuclAT_40 - -
- (2141709) 2141709..2141772 + 64 NuclAT_40 - -
- (2141709) 2141709..2141772 + 64 NuclAT_40 - -
NBY12_RS10285 (2142062) 2142062..2143162 - 1101 WP_250777705.1 sodium-potassium/proton antiporter ChaA -
NBY12_RS10290 (2143432) 2143432..2143662 + 231 WP_032302917.1 putative cation transport regulator ChaB -
NBY12_RS10295 (2143819) 2143819..2144514 + 696 WP_001295621.1 glutathione-specific gamma-glutamylcyclotransferase -
NBY12_RS10300 (2144558) 2144558..2144911 - 354 WP_001169669.1 DsrE/F sulfur relay family protein YchN -
NBY12_RS10305 (2145096) 2145096..2146490 + 1395 WP_032302918.1 inverse autotransporter invasin YchO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4041.88 Da        Isoelectric Point: 11.4779

>T247224 WP_000170956.1 NZ_CP098223:c2141656-2141549 [Escherichia coli]
MTLAQFAMIFWHDLAAPILAGIITAVIVSWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 62 bp

>AT247224 NZ_CP098223:2141709-2141770 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829G035

Antitoxin

Download structure file

References