Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4167329..4167587 Replicon chromosome
Accession NZ_CP098206
Organism Escherichia coli strain Z0117EC0054

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag NBY18_RS20400 Protein ID WP_000809168.1
Coordinates 4167435..4167587 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4167329..4167386 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY18_RS20385 4163161..4164420 - 1260 WP_000494924.1 hypothetical protein -
NBY18_RS20390 4164549..4166042 - 1494 WP_001350775.1 sulfatase-like hydrolase/transferase -
NBY18_RS20395 4166062..4166823 - 762 WP_001274823.1 outer membrane protein OmpK -
- 4167329..4167386 - 58 - - Antitoxin
NBY18_RS20400 4167435..4167587 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
NBY18_RS20405 4167692..4168822 - 1131 WP_001118464.1 molecular chaperone DnaJ -
NBY18_RS20410 4168911..4170827 - 1917 WP_167823494.1 molecular chaperone DnaK -
NBY18_RS20415 4171199..4171603 + 405 WP_000843687.1 DUF2541 family protein -
NBY18_RS20420 4171629..4172342 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T247068 WP_000809168.1 NZ_CP098206:4167435-4167587 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT247068 NZ_CP098206:c4167386-4167329 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References