Detailed information of TA system TA024702

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 12414..12949
• Replicon: chromosome
• Accession: NC_014012
• Organism: Shewanella violacea DSS12

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: D4ZD63
• Locus tag: SVI_RS00065
• Protein ID: WP_013049301.1
• Coordinates: 12414..12698 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: D4ZD64
• Locus tag: SVI_RS00070
• Protein ID: WP_013049302.1
• Coordinates: 12698..12949 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SVI_RS00040	7488..8189	+	702	WP_013049296.1	SCO family protein	-
SVI_RS00045	8326..9297	+	972	WP_013049297.1	nucleoside hydrolase	-
SVI_RS00050	9383..10027	-	645	WP_041420144.1	LysE family translocator	-
SVI_RS00055	10928..11152	+	225	WP_013049299.1	hypothetical protein	-
SVI_RS00060	11474..12403	+	930	WP_041419527.1	DUF1186 domain-containing protein	-
SVI_RS00065	12414..12698	-	285	WP_013049301.1	Txe/YoeB family addiction module toxin	Toxin
SVI_RS00070	12698..12949	-	252	WP_013049302.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
SVI_RS00075	13343..16504	-	3162	WP_041420145.1	DEAD/DEAH box helicase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (13-92)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11380.87 Da
• Isoelectric Point: 9.8837

>T24702 WP_013049301.1 NC_014012:c12698-12414 [Shewanella violacea DSS12]
MKTNTTTLFSTFYSEQAWNDYLYWQQQDKKTLKRINLLIKDCQRTPFEGIGKPERLKENLSGYWSRRISDEHRLVYRANQ
DQLTIVALRFHYSS

Nucleotide

• Length: 285 bp

>T24702 NC_014012:c12698-12414 [Shewanella violacea DSS12]
ATGAAAACTAATACAACTACCCTTTTCTCGACCTTTTATTCAGAGCAGGCCTGGAACGATTACCTTTATTGGCAACAACA
AGATAAAAAGACGTTAAAGCGAATTAACCTGCTTATTAAAGATTGCCAAAGAACACCTTTTGAGGGTATTGGCAAACCAG
AAAGGTTAAAAGAGAACCTTTCTGGTTACTGGTCTAGACGGATCTCCGATGAACATCGCTTAGTTTATAGGGCAAACCAG
GATCAATTAACAATTGTTGCCCTACGCTTCCATTACTCTTCCTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9481.58 Da
• Isoelectric Point: 4.4341

>AT24702 WP_013049302.1 NC_014012:c12949-12698 [Shewanella violacea DSS12]
MSVYSFTEVRSNFKSVCDSVVNDCEPAVIHRRGAENVVMFSESEFNSWKETIYLLSNPVNAKHLLDSIKQIDDGQAQERE
LLD

Nucleotide

• Length: 252 bp

>AT24702 NC_014012:c12949-12698 [Shewanella violacea DSS12]
ATGAGTGTTTATAGTTTTACTGAGGTAAGAAGTAATTTTAAATCTGTTTGTGACAGCGTGGTCAACGACTGCGAACCTGC
TGTAATACATCGTCGTGGCGCTGAAAATGTCGTCATGTTCTCTGAGTCAGAGTTCAATAGCTGGAAAGAAACTATCTACT
TACTTTCAAACCCAGTAAATGCAAAGCATCTGTTAGATTCTATAAAGCAGATTGATGATGGCCAAGCTCAAGAGCGAGAG
TTACTGGATTAA

Structures

Toxin

• AlphaFold DB: D4ZD63

Antitoxin

• AlphaFold DB: D4ZD64