Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 2584322..2585027 | Replicon | chromosome |
| Accession | NC_013959 | ||
| Organism | Sideroxydans lithotrophicus ES-1 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | D5CN76 |
| Locus tag | SLIT_RS12725 | Protein ID | WP_013030671.1 |
| Coordinates | 2584722..2585027 (-) | Length | 102 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | D5CN75 |
| Locus tag | SLIT_RS12720 | Protein ID | WP_013030670.1 |
| Coordinates | 2584322..2584720 (-) | Length | 133 a.a. |
Genomic Context
Location: 2579424..2581655 (2232 bp)
Type: Others
Protein ID: WP_013030667.1
Type: Others
Protein ID: WP_013030667.1
Location: 2581680..2583071 (1392 bp)
Type: Others
Protein ID: WP_013030668.1
Type: Others
Protein ID: WP_013030668.1
Location: 2583191..2584198 (1008 bp)
Type: Others
Protein ID: WP_013030669.1
Type: Others
Protein ID: WP_013030669.1
Location: 2584322..2584720 (399 bp)
Type: Antitoxin
Protein ID: WP_013030670.1
Type: Antitoxin
Protein ID: WP_013030670.1
Location: 2584722..2585027 (306 bp)
Type: Toxin
Protein ID: WP_013030671.1
Type: Toxin
Protein ID: WP_013030671.1
Location: 2585240..2585629 (390 bp)
Type: Others
Protein ID: WP_013030672.1
Type: Others
Protein ID: WP_013030672.1
Location: 2585677..2586306 (630 bp)
Type: Others
Protein ID: WP_013030673.1
Type: Others
Protein ID: WP_013030673.1
Location: 2586303..2587697 (1395 bp)
Type: Others
Protein ID: WP_013030674.1
Type: Others
Protein ID: WP_013030674.1
Location: 2587694..2589493 (1800 bp)
Type: Others
Protein ID: WP_013030675.1
Type: Others
Protein ID: WP_013030675.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SLIT_RS12705 | 2579424..2581655 | + | 2232 | WP_013030667.1 | methionine--tRNA ligase | - |
| SLIT_RS12710 | 2581680..2583071 | + | 1392 | WP_013030668.1 | Si-specific NAD(P)(+) transhydrogenase | - |
| SLIT_RS15385 | 2583191..2584198 | - | 1008 | WP_013030669.1 | hypothetical protein | - |
| SLIT_RS12720 | 2584322..2584720 | - | 399 | WP_013030670.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| SLIT_RS12725 | 2584722..2585027 | - | 306 | WP_013030671.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| SLIT_RS12730 | 2585240..2585629 | - | 390 | WP_013030672.1 | bacteriohemerythrin | - |
| SLIT_RS12735 | 2585677..2586306 | - | 630 | WP_013030673.1 | V-type ATP synthase subunit D | - |
| SLIT_RS12740 | 2586303..2587697 | - | 1395 | WP_013030674.1 | V-type ATP synthase subunit B | - |
| SLIT_RS12745 | 2587694..2589493 | - | 1800 | WP_013030675.1 | V-type ATP synthase subunit A | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2578757..2599551 | 20794 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11169.00 Da Isoelectric Point: 9.9453
>T24657 WP_013030671.1 NC_013959:c2585027-2584722 [Sideroxydans lithotrophicus ES-1]
MEKKKPHYPLSEVQRVVEDRGVNAFTATALIGAAALGLSVEQAVAVVLGLKQKDLYKSMTTNADHKIWQDVYHATLKSGL
VAYIKVTLRENGTVVIQFKEK
MEKKKPHYPLSEVQRVVEDRGVNAFTATALIGAAALGLSVEQAVAVVLGLKQKDLYKSMTTNADHKIWQDVYHATLKSGL
VAYIKVTLRENGTVVIQFKEK
Download Length: 306 bp
>T24657 NC_013959:c2585027-2584722 [Sideroxydans lithotrophicus ES-1]
ATGGAGAAAAAGAAACCGCATTACCCACTATCTGAAGTTCAACGAGTCGTTGAAGATCGCGGAGTCAATGCTTTTACCGC
TACTGCATTAATTGGCGCCGCCGCATTGGGGCTTTCAGTTGAGCAGGCGGTGGCTGTGGTTTTGGGACTCAAACAGAAGG
ATTTGTATAAGAGCATGACCACAAATGCCGATCACAAAATCTGGCAAGACGTGTATCACGCAACGTTGAAATCTGGATTG
GTGGCTTATATCAAAGTCACCTTGCGTGAAAACGGAACCGTTGTGATCCAATTTAAGGAGAAATGA
ATGGAGAAAAAGAAACCGCATTACCCACTATCTGAAGTTCAACGAGTCGTTGAAGATCGCGGAGTCAATGCTTTTACCGC
TACTGCATTAATTGGCGCCGCCGCATTGGGGCTTTCAGTTGAGCAGGCGGTGGCTGTGGTTTTGGGACTCAAACAGAAGG
ATTTGTATAAGAGCATGACCACAAATGCCGATCACAAAATCTGGCAAGACGTGTATCACGCAACGTTGAAATCTGGATTG
GTGGCTTATATCAAAGTCACCTTGCGTGAAAACGGAACCGTTGTGATCCAATTTAAGGAGAAATGA
Antitoxin
Download Length: 133 a.a. Molecular weight: 14800.11 Da Isoelectric Point: 8.8500
>AT24657 WP_013030670.1 NC_013959:c2584720-2584322 [Sideroxydans lithotrophicus ES-1]
MKHLCLNCEKGDMVRTKKDSEIEYRGHRAIVRALDGWHCPECGEVEFAGKEGVRYAEALEKLRLKIDAEESAELARIRKK
LKLSQRRAAAIAGGGVNAFSRYENGKARPVAAVVNLFRLLEKHPELLDEIAA
MKHLCLNCEKGDMVRTKKDSEIEYRGHRAIVRALDGWHCPECGEVEFAGKEGVRYAEALEKLRLKIDAEESAELARIRKK
LKLSQRRAAAIAGGGVNAFSRYENGKARPVAAVVNLFRLLEKHPELLDEIAA
Download Length: 399 bp
>AT24657 NC_013959:c2584720-2584322 [Sideroxydans lithotrophicus ES-1]
ATGAAACACCTGTGCCTGAATTGCGAAAAAGGCGACATGGTCCGCACCAAAAAAGATTCAGAGATTGAATATCGTGGCCA
CCGCGCCATTGTTCGTGCGCTGGATGGTTGGCATTGCCCTGAGTGCGGAGAGGTCGAGTTTGCTGGTAAGGAAGGTGTGC
GTTATGCAGAAGCCTTGGAAAAGCTGCGGCTGAAAATTGACGCAGAAGAATCCGCAGAACTGGCGCGAATTCGGAAAAAA
CTTAAGCTTTCGCAACGCCGTGCAGCTGCTATTGCCGGTGGCGGTGTCAATGCCTTTTCTCGATACGAAAATGGCAAAGC
GAGACCCGTGGCTGCAGTGGTCAACTTGTTCCGTCTATTGGAAAAACATCCTGAGTTACTTGACGAGATTGCGGCTTAG
ATGAAACACCTGTGCCTGAATTGCGAAAAAGGCGACATGGTCCGCACCAAAAAAGATTCAGAGATTGAATATCGTGGCCA
CCGCGCCATTGTTCGTGCGCTGGATGGTTGGCATTGCCCTGAGTGCGGAGAGGTCGAGTTTGCTGGTAAGGAAGGTGTGC
GTTATGCAGAAGCCTTGGAAAAGCTGCGGCTGAAAATTGACGCAGAAGAATCCGCAGAACTGGCGCGAATTCGGAAAAAA
CTTAAGCTTTCGCAACGCCGTGCAGCTGCTATTGCCGGTGGCGGTGTCAATGCCTTTTCTCGATACGAAAATGGCAAAGC
GAGACCCGTGGCTGCAGTGGTCAACTTGTTCCGTCTATTGGAAAAACATCCTGAGTTACTTGACGAGATTGCGGCTTAG