Detailed information of TA system TA246564

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-ratA/Fst(toxin)
• Location: 20087..20328
• Replicon: plasmid pQZ076-3
• Accession: NZ_CP098028
• Organism: Enterococcus faecalis strain QZ076

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: NAG05_RS15525
• Protein ID: WP_002360667.1
• Coordinates: 20087..20197 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	20237..20328 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NAG05_RS15485 (15168)	15168..15398	-	231	WP_002362431.1	hypothetical protein	-
NAG05_RS15490 (15602)	15602..16222	+	621	WP_162500025.1	recombinase family protein	-
NAG05_RS15495 (16239)	16239..16403	+	165	WP_250652966.1	hypothetical protein	-
NAG05_RS15505 (17807)	17807..18040	+	234	WP_002394799.1	hypothetical protein	-
NAG05_RS15510 (18200)	18200..18454	-	255	WP_002394800.1	hypothetical protein	-
NAG05_RS15515 (18571)	18571..19239	-	669	WP_002403283.1	CPBP family intramembrane metalloprotease	-
NAG05_RS15520 (19275)	19275..19592	-	318	WP_002394802.1	heavy metal-binding domain-containing protein	-
NAG05_RS15525 (20087)	20087..20197	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (20237)	20237..20328	-	92	NuclAT_0	-	Antitoxin
- (20237)	20237..20328	-	92	NuclAT_0	-	Antitoxin
- (20237)	20237..20328	-	92	NuclAT_0	-	Antitoxin
- (20237)	20237..20328	-	92	NuclAT_0	-	Antitoxin
NAG05_RS15530 (20437)	20437..20736	+	300	WP_010817802.1	hypothetical protein	-
NAG05_RS15535 (21521)	21521..22063	-	543	WP_086321354.1	hypothetical protein	-
NAG05_RS15540 (22073)	22073..22924	-	852	WP_002362419.1	ParA family protein	-
NAG05_RS15545 (23587)	23587..24603	+	1017	WP_033593833.1	replication initiator protein A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	dfrG / aph(3')-III / erm(B)	-	1..55867	55867

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T246564 WP_002360667.1 NZ_CP098028:20087-20197 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 92 bp

>AT246564 NZ_CP098028:c20328-20237 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin