Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2889297..2889634 Replicon chromosome
Accession NZ_CP098025
Organism Enterococcus faecalis strain QZ076

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag NAG05_RS14280 Protein ID WP_002396786.1
Coordinates 2889297..2889440 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2889372..2889634 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAG05_RS14265 (2885013) 2885013..2885645 - 633 WP_002358972.1 RloB family protein -
NAG05_RS14270 (2885654) 2885654..2886949 - 1296 WP_002410675.1 ATP-binding protein -
NAG05_RS14275 (2887411) 2887411..2889027 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
NAG05_RS14280 (2889297) 2889297..2889440 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2889584) 2889584..2889633 + 50 NuclAT_8 - -
- (2889372) 2889372..2889634 - 263 NuclAT_7 - Antitoxin
NAG05_RS14285 (2889635) 2889635..2894326 - 4692 WP_250652880.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T246556 WP_002396786.1 NZ_CP098025:2889297-2889440 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT246556 NZ_CP098025:c2889634-2889372 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGACAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References