Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1035442..1035944 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag M9782_RS04625 Protein ID WP_039282578.1
Coordinates 1035442..1035696 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag M9782_RS04630 Protein ID WP_039324900.1
Coordinates 1035693..1035944 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS04605 (M9782_04605) 1030596..1031858 - 1263 WP_275071756.1 L-rhamnose isomerase -
M9782_RS04610 (M9782_04610) 1031855..1033345 - 1491 WP_275071757.1 rhamnulokinase -
M9782_RS04615 (M9782_04615) 1033682..1034521 + 840 WP_275071758.1 HTH-type transcriptional activator RhaS -
M9782_RS04620 (M9782_04620) 1034546..1035400 + 855 WP_275071759.1 helix-turn-helix domain-containing protein -
M9782_RS04625 (M9782_04625) 1035442..1035696 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
M9782_RS04630 (M9782_04630) 1035693..1035944 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
M9782_RS04635 (M9782_04635) 1036020..1037723 - 1704 WP_275071760.1 ABC transporter ATP-binding protein -
M9782_RS04640 (M9782_04640) 1037720..1038586 - 867 WP_039355015.1 ABC transporter permease -
M9782_RS04645 (M9782_04645) 1038579..1039538 - 960 WP_275071761.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T246518 WP_039282578.1 NZ_CP097896:c1035696-1035442 [Pectobacterium actinidiae]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT246518 WP_039324900.1 NZ_CP097896:c1035944-1035693 [Pectobacterium actinidiae]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References