246514

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 594727..596078 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag M9782_RS02615 Protein ID WP_275071595.1
Coordinates 594727..595767 (-) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag M9782_RS02620 Protein ID WP_275071596.1
Coordinates 595764..596078 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS02585 (M9782_02585) 589840..591192 + 1353 WP_275071590.1 glutathione-disulfide reductase -
M9782_RS02590 (M9782_02590) 591286..591573 - 288 WP_039363923.1 type II toxin-antitoxin system RelE/ParE family toxin -
M9782_RS02595 (M9782_02595) 591570..591821 - 252 WP_275071591.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
M9782_RS02600 (M9782_02600) 592076..592981 + 906 WP_275071592.1 siderophore-interacting protein -
M9782_RS02605 (M9782_02605) 593016..593771 - 756 WP_275071593.1 thiol:disulfide interchange protein DsbG -
M9782_RS02610 (M9782_02610) 594044..594667 + 624 WP_275071594.1 LysE family translocator -
M9782_RS02615 (M9782_02615) 594727..595767 - 1041 WP_275071595.1 HipA domain-containing protein Toxin
M9782_RS02620 (M9782_02620) 595764..596078 - 315 WP_275071596.1 HipA N-terminal domain-containing protein Antitoxin
M9782_RS02625 (M9782_02625) 596063..596389 - 327 WP_039363945.1 helix-turn-helix domain-containing protein -
M9782_RS02630 (M9782_02630) 596576..597709 - 1134 WP_275071597.1 alkylhydroperoxidase domain protein -
M9782_RS02635 (M9782_02635) 597706..598740 - 1035 WP_039363951.1 putative FMN-dependent luciferase-like monooxygenase -
M9782_RS02640 (M9782_02640) 598742..600445 - 1704 WP_275071598.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39494.36 Da        Isoelectric Point: 6.6650

>T246514 WP_275071595.1 NZ_CP097896:c595767-594727 [Pectobacterium actinidiae]
MTRCRILLTPLTHEEESATGYSRKGLKHLTGSMHASPTLRFTRQQFMHDLPQAQKGMSISGYQPKIQMVLEERAFTVVDH
QGLYILKPSPSEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDENTGHPIHQEQLDGAMG
IGEKFGKIHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGSLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDKALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFIKEAECVESTYRDSFMP
AEAIETTLRCYRHRLNLMSILDADRI

Download         Length: 1041 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11837.54 Da        Isoelectric Point: 8.3628

>AT246514 WP_275071596.1 NZ_CP097896:c596078-595764 [Pectobacterium actinidiae]
VRRQVKVYLYGVHIGQLSQDDDGYLFEYKQSYIGPPLSLSLPIQTGTFRSQTLPPYFASLAPEGWLRRQYSKLQHLDEKD
LFGILIQNGKNLIGAVQLIGEDKP

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References