246391

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 6654707..6655302 Replicon chromosome
Accession NZ_CP097857
Organism Pseudomonas sp. B111

Toxin (Protein)


Gene name higB Uniprot ID A0A9E8L6K5
Locus tag M6E97_RS31005 Protein ID WP_071534386.1
Coordinates 6655024..6655302 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag M6E97_RS31000 Protein ID WP_003133769.1
Coordinates 6654707..6655012 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M6E97_RS30965 (M6E97_30925) 6650653..6650943 - 291 WP_023119949.1 DUF5447 family protein -
M6E97_RS30970 (M6E97_30930) 6650947..6651129 - 183 WP_058187913.1 hypothetical protein -
M6E97_RS30975 (M6E97_30935) 6651119..6651391 - 273 WP_004352675.1 hypothetical protein -
M6E97_RS30980 (M6E97_30940) 6651501..6651767 + 267 WP_023088595.1 hypothetical protein -
M6E97_RS30985 (M6E97_30945) 6651823..6652158 + 336 WP_031637200.1 hypothetical protein -
M6E97_RS30990 (M6E97_30950) 6652311..6653528 + 1218 WP_071534385.1 AAA family ATPase -
M6E97_RS30995 (M6E97_30955) 6653529..6654257 + 729 WP_152904799.1 hypothetical protein -
M6E97_RS31000 (M6E97_30960) 6654707..6655012 - 306 WP_003133769.1 HigA family addiction module antitoxin Antitoxin
M6E97_RS31005 (M6E97_30965) 6655024..6655302 - 279 WP_071534386.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M6E97_RS31010 (M6E97_30970) 6655355..6655477 - 123 Protein_6131 integrase -
M6E97_RS31015 (M6E97_30975) 6655625..6657853 + 2229 WP_034005476.1 TonB-dependent receptor -
M6E97_RS31020 (M6E97_30980) 6657923..6658570 - 648 WP_003095021.1 carbonate dehydratase -
M6E97_RS31025 (M6E97_30985) 6658632..6659870 - 1239 WP_003111578.1 C69 family dipeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(5-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-82)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10698.23 Da        Isoelectric Point: 7.9184

>T246391 WP_071534386.1 NZ_CP097857:c6655302-6655024 [Pseudomonas sp. B111]
MILTFRCDETRQLFETGLSRRWGAILTVATRKLAMHHAATELRDLRSPPGNRLEPLQGKRVGQHSIRINDQWRVCFVWTD
AGPEEVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11214.73 Da        Isoelectric Point: 4.6081

>AT246391 WP_003133769.1 NZ_CP097857:c6655012-6654707 [Pseudomonas sp. B111]
MATNGMRPIHPGEILRDEFLMELDISPAALARALKVSAPTVNDIVREQRGISADMAIRLGRYFDTSAQFWMNLQSEYSLA
TAYAANGEQIEHEIEPLLAHG

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References