Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3952440..3952698 Replicon chromosome
Accession NZ_CP097724
Organism Escherichia coli strain MS1494

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag M9O75_RS19190 Protein ID WP_000809168.1
Coordinates 3952546..3952698 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3952440..3952497 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9O75_RS19175 3948269..3949528 - 1260 WP_000494928.1 hypothetical protein -
M9O75_RS19180 3949657..3951150 - 1494 WP_001468392.1 sulfatase-like hydrolase/transferase -
M9O75_RS19185 3951170..3951931 - 762 WP_001274832.1 outer membrane protein OmpK -
- 3952440..3952497 - 58 - - Antitoxin
M9O75_RS19190 3952546..3952698 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
M9O75_RS19195 3952803..3953933 - 1131 WP_001118464.1 molecular chaperone DnaJ -
M9O75_RS19200 3954022..3955938 - 1917 WP_000516135.1 molecular chaperone DnaK -
M9O75_RS19205 3956311..3956715 + 405 WP_000843687.1 DUF2541 family protein -
M9O75_RS19210 3956741..3957454 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T246188 WP_000809168.1 NZ_CP097724:3952546-3952698 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT246188 NZ_CP097724:c3952497-3952440 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References