Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1858060..1858763 Replicon chromosome
Accession NZ_CP097636
Organism Aquincola tertiaricarbonis strain RN12

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag MW290_RS22890 Protein ID WP_250199953.1
Coordinates 1858060..1858359 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag MW290_RS22895 Protein ID WP_250199954.1
Coordinates 1858362..1858763 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MW290_RS22865 (MW290_22865) 1853969..1854892 + 924 WP_250199948.1 LysR family transcriptional regulator -
MW290_RS22870 (MW290_22870) 1854908..1855909 - 1002 WP_250199949.1 tripartite tricarboxylate transporter substrate binding protein -
MW290_RS22875 (MW290_22875) 1855954..1856481 - 528 WP_250199950.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
MW290_RS22880 (MW290_22880) 1856570..1857562 + 993 WP_250199951.1 LysR family transcriptional regulator -
MW290_RS22885 (MW290_22885) 1857578..1857943 - 366 WP_250199952.1 translation initiation factor Sui1 -
MW290_RS22890 (MW290_22890) 1858060..1858359 + 300 WP_250199953.1 type II toxin-antitoxin system MqsR family toxin Toxin
MW290_RS22895 (MW290_22895) 1858362..1858763 + 402 WP_250199954.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
MW290_RS22900 (MW290_22900) 1858802..1859836 + 1035 WP_250199955.1 RNA methyltransferase -
MW290_RS22905 (MW290_22905) 1859852..1861186 - 1335 WP_250199956.1 sorbosone dehydrogenase family protein -
MW290_RS22910 (MW290_22910) 1861386..1861634 + 249 WP_250199957.1 hypothetical protein -
MW290_RS22915 (MW290_22915) 1861645..1862142 + 498 WP_250199958.1 hypothetical protein -
MW290_RS22920 (MW290_22920) 1862164..1862661 - 498 WP_250199959.1 M48 family metallopeptidase -
MW290_RS22925 (MW290_22925) 1862678..1863268 - 591 WP_250199960.1 malonic semialdehyde reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-98)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11364.31 Da        Isoelectric Point: 9.1038

>T245706 WP_250199953.1 NZ_CP097636:1858060-1858359 [Aquincola tertiaricarbonis]
MEKRTPHCKLRVVKQMVTEGLCEATITALGTAREMGLGFSDMKRELLRLEAPSFYKSMTTHADHRLWQDVYRHTLESGLK
AYVKLTVHEGVLIVSFKEL

Download         Length: 300 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14614.85 Da        Isoelectric Point: 8.8285

>AT245706 WP_250199954.1 NZ_CP097636:1858362-1858763 [Aquincola tertiaricarbonis]
MKCPHCGGASMAADTRDVAYTYKGRDTVIPQVTGRFCPACGEVLLAGEHAERYSDLVGRFHREVNATLVDPAYIAKVRRK
LALDQREAAEIFGGGVNAFSRYETGKTKPPVALMKLLKVLDRHPELLQEVRAG

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References