Detailed information of TA system TA245669

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 1882197..1882929
• Replicon: chromosome
• Accession: NZ_CP097618
• Organism: Pasteurella multocida strain P2095

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: M8854_RS08755
• Protein ID: WP_064965342.1
• Coordinates: 1882197..1882523 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: M8854_RS08760
• Protein ID: WP_005757699.1
• Coordinates: 1882603..1882929 (+)
• Length: 109 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (12-104)

Antitoxin

• Toxin-antitoxin system, antidote protein, HigA (1-102)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12846.66 Da
• Isoelectric Point: 9.6705

>T245669 WP_064965342.1 NZ_CP097618:1882197-1882523 [Pasteurella multocida]
MDRVRFNLTEDSFQDKYLYEYFLYGSKHKNIPSDIENTLAHKLDMLDSANTLSDLRSPPGNKLEKLEPKTTGLYSIRVNV
KYRLIFKYKESNSPKITELRLDKHQYRL

Nucleotide

• Length: 327 bp

Antitoxin

Protein

• Length: 109 a.a.
• Molecular weight: 12377.41 Da
• Isoelectric Point: 7.2034

>AT245669 WP_005757699.1 NZ_CP097618:1882603-1882929 [Pasteurella multocida]
MSRVQRKPSTVGDILLDEYLVPLNLKIADLATMLDVHRNTASALVNNNTKLSLEMALKLAKLFNTSPEFWLNLQMKLDLW
EIENNARFQESLKKISSIDQHNLLEKIA

Nucleotide

• Length: 327 bp