Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3523943..3524778 Replicon chromosome
Accession NZ_CP097576
Organism Microcystis aeruginosa str. Chao 1910

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag M8120_RS17745 Protein ID WP_190359397.1
Coordinates 3523943..3524440 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag M8120_RS17750 Protein ID WP_190359396.1
Coordinates 3524443..3524778 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8120_RS17710 (M8120_17555) 3519953..3520672 - 720 WP_190359399.1 PEP-CTERM sorting domain-containing protein -
M8120_RS17715 (M8120_17560) 3521098..3521400 + 303 WP_079209850.1 hypothetical protein -
M8120_RS17720 (M8120_17565) 3521375..3521734 + 360 WP_079209849.1 DUF5615 family PIN-like protein -
M8120_RS17725 (M8120_17570) 3521860..3522111 - 252 WP_004162546.1 type II toxin-antitoxin system RelE/ParE family toxin -
M8120_RS17730 (M8120_17575) 3522090..3522284 - 195 WP_004162545.1 hypothetical protein -
M8120_RS17735 (M8120_17580) 3522704..3522955 + 252 WP_002764591.1 UPF0175 family protein -
M8120_RS17740 (M8120_17585) 3522948..3523436 + 489 WP_190359398.1 DUF3368 domain-containing protein -
M8120_RS17745 (M8120_17590) 3523943..3524440 - 498 WP_190359397.1 type II toxin-antitoxin system YhaV family toxin Toxin
M8120_RS17750 (M8120_17595) 3524443..3524778 - 336 WP_190359396.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
M8120_RS17755 (M8120_17600) 3525053..3526231 + 1179 WP_190359395.1 AI-2E family transporter -
M8120_RS17760 (M8120_17605) 3527302..3527811 + 510 WP_004162542.1 inorganic diphosphatase -
M8120_RS17765 3527835..3527966 + 132 WP_265795409.1 hypothetical protein -
M8120_RS17770 (M8120_17610) 3527957..3528640 + 684 WP_190359394.1 N-acetylmannosamine-6-phosphate 2-epimerase -
M8120_RS17775 (M8120_17615) 3528681..3528749 - 69 Protein_3524 DUF4164 domain-containing protein -
M8120_RS17780 (M8120_17620) 3528727..3528876 + 150 WP_265795410.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(14-151)

Antitoxin

PrlF antitoxin

(10-108)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 19673.28 Da        Isoelectric Point: 8.3818

>T245628 WP_190359397.1 NZ_CP097576:c3524440-3523943 [Microcystis aeruginosa str. Chao 1910]
MSIDQPLIINGWNIFAHPLFLEQFEELVTQVEELRHKFPKDYKRKNATKRLAAIAKLAFDTIPQDPTRSDYRQGTALGDD
YKHWFRAKFFQQYRLFFRYHQESKIILLAWVNDENSKRAYESSTDAYRVFRKMLETGHPPDDWNDLLKEAKSTISRLREA
AETEI

Download         Length: 498 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12412.93 Da        Isoelectric Point: 4.1961

>AT245628 WP_190359396.1 NZ_CP097576:c3524778-3524443 [Microcystis aeruginosa str. Chao 1910]
MAATMAPCPESTLTDRYQTTIPDSVRKALGLNKRDKICYNIQPDGKVWISRADGTEENDPVLGKFLNFLAQDMEQNPQHI
QPISSNLVNHVQYLVSGVDLELDAPLLDEDE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References