245598

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2484992..2485176 Replicon chromosome
Accession NZ_CP097571
Organism Staphylococcus aureus strain V40

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag M8789_RS12400 Protein ID WP_000482647.1
Coordinates 2485069..2485176 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2484992..2485052 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M8789_RS12385 2480446..2480613 - 168 WP_031927726.1 hypothetical protein -
M8789_RS12390 2480844..2482577 - 1734 WP_000486497.1 ABC transporter ATP-binding protein -
M8789_RS12395 2482602..2484365 - 1764 WP_001064840.1 ABC transporter ATP-binding protein -
- 2484992..2485052 + 61 - - Antitoxin
M8789_RS12400 2485069..2485176 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
M8789_RS12405 2485310..2485696 - 387 WP_000779353.1 flippase GtxA -
M8789_RS12410 2485964..2487106 + 1143 WP_001176867.1 glycerate kinase -
M8789_RS12415 2487166..2487825 + 660 WP_000831298.1 membrane protein -
M8789_RS12420 2488008..2489219 + 1212 WP_001191927.1 multidrug effflux MFS transporter -
M8789_RS12425 2489342..2489815 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T245598 WP_000482647.1 NZ_CP097571:c2485176-2485069 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT245598 NZ_CP097571:2484992-2485052 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References