Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 638909..639583 Replicon chromosome
Accession NZ_CP097329
Organism Pseudanabaena mucicola str. Chao 1806

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag M4D78_RS03115 Protein ID WP_286394491.1
Coordinates 639311..639583 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag M4D78_RS03110 Protein ID WP_286394489.1
Coordinates 638909..639220 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4D78_RS03080 634211..634459 + 249 WP_286394478.1 transposase -
M4D78_RS03085 634732..635388 + 657 WP_286394480.1 DUF2834 domain-containing protein -
M4D78_RS03090 636107..636520 + 414 WP_286394481.1 DUF2358 domain-containing protein -
M4D78_RS03095 636665..637471 + 807 WP_286394484.1 DUF1838 domain-containing protein -
M4D78_RS03100 637541..637915 + 375 WP_286394486.1 diacylglycerol kinase -
M4D78_RS03105 638113..638904 - 792 WP_286394488.1 TlyA family RNA methyltransferase -
M4D78_RS03110 638909..639220 - 312 WP_286394489.1 HigA family addiction module antitoxin Antitoxin
M4D78_RS03115 639311..639583 - 273 WP_286394491.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M4D78_RS03120 639839..640501 - 663 WP_286394493.1 TMEM165/GDT1 family protein -
M4D78_RS03125 641302..642936 + 1635 WP_286394494.1 alpha-D-glucose phosphate-specific phosphoglucomutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-90)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(13-90)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10645.21 Da        Isoelectric Point: 9.9787

>T245162 WP_286394491.1 NZ_CP097329:c639583-639311 [Pseudanabaena mucicola str. Chao 1806]
MIKNFKNKLLESLLNGDMQPTTKEHKKVQIRLEHIDSASKIENLKLPRYDLHKLKGNKKGVWSIKTTGNWLITFRFEDGH
AYDVNHEDYH

Download         Length: 273 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11823.65 Da        Isoelectric Point: 6.4738

>AT245162 WP_286394489.1 NZ_CP097329:c639220-638909 [Pseudanabaena mucicola str. Chao 1806]
MNELLESLKNRKTRPVHPGEVILDILEDIEISQTQFAKMLGVSRRTVNQIIRGHRPVTVDMAIRIGKALGNGPESWLNLQ
QKVDLWDALQKYEEEYEKVLTVA

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References