245155

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 910775..911279 Replicon chromosome
Accession NZ_CP097327
Organism Providencia vermicola strain P13

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag M5J11_RS04415 Protein ID WP_282560439.1
Coordinates 911022..911279 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag M5J11_RS04410 Protein ID WP_196714179.1
Coordinates 910775..911029 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5J11_RS04390 (M5J11_04390) 906447..906875 + 429 WP_251464799.1 protein tyrosine phosphatase -
M5J11_RS04395 (M5J11_04395) 906909..908987 + 2079 WP_251464800.1 polysaccharide biosynthesis tyrosine autokinase -
M5J11_RS04400 (M5J11_04400) 909005..910030 + 1026 WP_251464801.1 UDP-glucose 4-epimerase GalE -
M5J11_RS04405 (M5J11_04405) 910193..910696 + 504 WP_154624169.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
M5J11_RS04410 (M5J11_04410) 910775..911029 + 255 WP_196714179.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M5J11_RS04415 (M5J11_04415) 911022..911279 + 258 WP_282560439.1 Txe/YoeB family addiction module toxin Toxin
M5J11_RS04420 (M5J11_04420) 911388..912209 - 822 WP_154624171.1 serine O-acetyltransferase -
M5J11_RS04425 (M5J11_04425) 912235..913263 - 1029 WP_154624172.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
M5J11_RS04430 (M5J11_04430) 913272..913739 - 468 WP_154624173.1 protein-export chaperone SecB -
M5J11_RS04435 (M5J11_04435) 913859..914296 - 438 WP_154624174.1 rhodanese-like domain-containing protein -
M5J11_RS04440 (M5J11_04440) 914793..916085 + 1293 WP_163863391.1 murein hydrolase activator EnvC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element sul1 / qacE / lnu(F) / aadA2 / floR / sul2 / aph(4)-Ia / aac(3)-IVa / aph(3')-Ia / msr(E) / mph(E) / blaNDM-1 / dfrA1 / ant(3'')-Ia / blaOXA-10 / catB8 / ant(2'')-Ia rfaD / ugd 830188..1088753 258565


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10140.63 Da        Isoelectric Point: 8.8172

>T245155 WP_282560439.1 NZ_CP097327:911022-911279 [Providencia vermicola]
MSRFLITDQGWEDYLYRQTQDKKMLKRINKLIDETKRTPFYGIGKPEPLKENLAGFWSRRIDETNRLIYSIDDEGLTIIA
CRYY

Download         Length: 258 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9477.79 Da        Isoelectric Point: 5.8373

>AT245155 WP_196714179.1 NZ_CP097327:910775-911029 [Providencia vermicola]
MKTISFSEARNNLKSVLDKVVDDADTTIITPRDSEDAGVMSLEYYNSLMETIYLLRSPANAEHLNKSIAQFKAGKVKKRE
LINE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References