Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4481731..4481989 Replicon chromosome
Accession NC_013716
Organism Citrobacter rodentium ICC168

Toxin (Protein)


Gene name hokA Uniprot ID -
Locus tag ROD_RS20925 Protein ID WP_012908187.1
Coordinates 4481837..4481989 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokA
Locus tag -
Coordinates 4481731..4481786 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ROD_RS20905 4476950..4477945 - 996 WP_012908184.1 acyltransferase -
ROD_RS20910 4478120..4478422 + 303 WP_012908185.1 membrane protein -
ROD_RS20915 4478517..4479428 + 912 WP_001168551.1 glycine--tRNA ligase subunit alpha -
ROD_RS20920 4479438..4481507 + 2070 WP_012908186.1 glycine--tRNA ligase subunit beta -
- 4481731..4481786 - 56 - - Antitoxin
ROD_RS20925 4481837..4481989 + 153 WP_012908187.1 type I toxin-antitoxin system toxin HokA Toxin
ROD_RS20930 4482120..4482656 - 537 WP_012908188.1 copper-binding periplasmic metallochaperone CueP -
ROD_RS20935 4482810..4483022 - 213 WP_012908189.1 RNA chaperone/antiterminator CspA -
ROD_RS20940 4483290..4483580 - 291 WP_024133013.1 HTH-type transcriptional regulator -
ROD_RS20945 4483834..4485204 - 1371 WP_012908191.1 MFS transporter -
ROD_RS20950 4485645..4486355 + 711 WP_012908192.1 DUF3053 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(7-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5722.96 Da        Isoelectric Point: 6.8709

>T24513 WP_012908187.1 NC_013716:4481837-4481989 [Citrobacter rodentium ICC168]
MPQKCILCSLIVICLTILLFTWMVRDSLCELHIRQGNNELAAFLACEVKQ

Download         Length: 153 bp

>T24513 NC_013716:4481837-4481989 [Citrobacter rodentium ICC168]
ATGCCGCAAAAATGTATATTATGCAGTTTAATAGTGATATGTCTCACTATATTATTATTTACCTGGATGGTTCGTGATTC
ATTATGCGAATTACATATCAGACAGGGCAATAATGAACTGGCGGCATTTTTAGCCTGTGAAGTGAAACAGTAA

Antitoxin


Download         Length: 56 bp

>AT24513 NC_013716:c4481786-4481731 [Citrobacter rodentium ICC168]
GTTCATGCATAGAGGTGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References