Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-chpS/PRK09812-ChpS
Location 5675444..5676021 Replicon chromosome
Accession NZ_CP097286
Organism Pseudomonas viridiflava strain JACO-C-5

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag M4X66_RS25165 Protein ID WP_249583288.1
Coordinates 5675695..5676021 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag M4X66_RS25160 Protein ID WP_122445782.1
Coordinates 5675444..5675698 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4X66_RS25140 5670968..5672359 + 1392 WP_249583286.1 heavy metal sensor histidine kinase -
M4X66_RS25145 5672457..5672858 + 402 WP_057408846.1 MAPEG family protein -
M4X66_RS25150 5673056..5673463 - 408 WP_025995654.1 DUF1090 domain-containing protein -
M4X66_RS25155 5673518..5675200 - 1683 WP_249583287.1 NAD-dependent DNA ligase LigB -
M4X66_RS25160 5675444..5675698 + 255 WP_122445782.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
M4X66_RS25165 5675695..5676021 + 327 WP_249583288.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
M4X66_RS25170 5675966..5677156 - 1191 WP_249583289.1 methionine adenosyltransferase -
M4X66_RS25175 5677177..5678172 - 996 WP_192020852.1 metalloregulator ArsR/SmtB family transcription factor -
M4X66_RS25180 5678431..5680428 + 1998 WP_249583290.1 transketolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-74)

Antitoxin

SpoVT-AbrB domain

(6-48)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11885.55 Da        Isoelectric Point: 12.5044

>T245101 WP_249583288.1 NZ_CP097286:5675695-5676021 [Pseudomonas viridiflava]
VKQHGFNRADIVRISLNPTAGREQQRDFRPALVLTPAAYNVSGLAIVAPIIQGGDFARYSGFAVPLGGSGVPNKSPRRLT
SPGAFDDRRRITGRQQRAGRRRGRFFPR

Download         Length: 327 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9219.65 Da        Isoelectric Point: 4.6471

>AT245101 WP_122445782.1 NZ_CP097286:5675444-5675698 [Pseudomonas viridiflava]
MEVKIQQWGNSAAIRLPANVLKQMSLVSGDVLVLDVSSEVMTLRPAKARLHYQLADLMAQCDLNASEPEELAGWNAMQPI
GREA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References