Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5414720..5415313 Replicon chromosome
Accession NZ_CP097286
Organism Pseudomonas viridiflava strain JACO-C-5

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag M4X66_RS23910 Protein ID WP_074454419.1
Coordinates 5414720..5414998 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag M4X66_RS23915 Protein ID WP_025993256.1
Coordinates 5415008..5415313 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4X66_RS23885 5409847..5410743 + 897 WP_249583195.1 aspartyl/asparaginyl beta-hydroxylase domain-containing protein -
M4X66_RS23890 5411417..5411728 + 312 WP_249584765.1 hypothetical protein -
M4X66_RS23895 5412159..5412482 + 324 WP_058430394.1 helix-turn-helix domain-containing protein -
M4X66_RS23900 5412472..5413779 + 1308 WP_249583196.1 type II toxin-antitoxin system HipA family toxin -
M4X66_RS23905 5413810..5414433 - 624 WP_249583197.1 hypothetical protein -
M4X66_RS23910 5414720..5414998 + 279 WP_074454419.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M4X66_RS23915 5415008..5415313 + 306 WP_025993256.1 HigA family addiction module antitoxin Antitoxin
M4X66_RS23920 5415337..5415603 - 267 WP_004887407.1 accessory factor UbiK family protein -
M4X66_RS23925 5416023..5416361 + 339 WP_002555808.1 P-II family nitrogen regulator -
M4X66_RS23930 5416396..5417733 + 1338 WP_004887406.1 ammonium transporter -
M4X66_RS23935 5417975..5418400 + 426 WP_025993253.1 secondary thiamine-phosphate synthase enzyme YjbQ -
M4X66_RS23940 5418500..5418829 + 330 WP_004887402.1 transcriptional regulator SutA -
M4X66_RS23945 5418908..5419600 - 693 WP_249583198.1 HAD-IA family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(10-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-92)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10417.00 Da        Isoelectric Point: 7.8920

>T245100 WP_074454419.1 NZ_CP097286:5414720-5414998 [Pseudomonas viridiflava]
MIVSFKCGDTRGLFQHGKTRLWPALKAVAERKLAMLDAAVLLSDLRSPPGNRLEILDGDRRGQHSIRINAQFRICFVWGE
NGPEDVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11245.07 Da        Isoelectric Point: 8.5205

>AT245100 WP_025993256.1 NZ_CP097286:5415008-5415313 [Pseudomonas viridiflava]
MTKNGMRPVHPGEVLKEEYLEPMGLTAAALARALNVSTPTVNDIVLQRRGVSADVALRLGVCLETSPEFWLNLQLTYDLR
KAEIEKGAQIRDQVRRLARCA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References