Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 6469773..6470275 Replicon chromosome
Accession NZ_CP097263
Organism Kutzneria chonburiensis strain SMC256

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag M3Q35_RS29435 Protein ID WP_273935812.1
Coordinates 6470012..6470275 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag M3Q35_RS29430 Protein ID WP_273935811.1
Coordinates 6469773..6470015 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3Q35_RS29395 6465946..6466485 + 540 WP_273944504.1 DUF1707 domain-containing protein -
M3Q35_RS29400 6466472..6466741 + 270 WP_273935805.1 hypothetical protein -
M3Q35_RS29405 6466752..6467273 + 522 WP_273935806.1 GNAT family N-acetyltransferase -
M3Q35_RS29410 6467280..6467867 + 588 WP_273935807.1 DUF3558 domain-containing protein -
M3Q35_RS29415 6467971..6468330 + 360 WP_273935808.1 transcriptional regulator -
M3Q35_RS29420 6468330..6468893 + 564 WP_273935809.1 PPE domain-containing protein -
M3Q35_RS29425 6468896..6469669 + 774 WP_273935810.1 ESX secretion-associated protein EspG -
M3Q35_RS29430 6469773..6470015 + 243 WP_273935811.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M3Q35_RS29435 6470012..6470275 + 264 WP_273935812.1 Txe/YoeB family addiction module toxin Toxin
M3Q35_RS29440 6470349..6472037 - 1689 WP_273944505.1 glycerol-3-phosphate dehydrogenase/oxidase -
M3Q35_RS29445 6472276..6473022 + 747 WP_273935813.1 MIP/aquaporin family protein -
M3Q35_RS29450 6473043..6474545 + 1503 WP_273935814.1 glycerol kinase GlpK -
M3Q35_RS29455 6474645..6475247 - 603 WP_273935815.1 class F sortase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10455.79 Da        Isoelectric Point: 8.8699

>T245092 WP_273935812.1 NZ_CP097263:6470012-6470275 [Kutzneria chonburiensis]
MKLVWDELAWADYAWWQSEDRKVLKRIDALIKDTERNGNEGVGKPEALKHGFQGYWSRRITDEHRLVYKRAGHEIRIAAC
HYHYERS

Download         Length: 264 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8971.88 Da        Isoelectric Point: 4.4098

>AT245092 WP_273935811.1 NZ_CP097263:6469773-6470015 [Kutzneria chonburiensis]
MSYSESRANYAETLDAVVNDREEVVITRAGHEPVVIVSLDDYQSLKETAYLLRSPENARRLITAIERLESGGGEHHELAE

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References