Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2443856..2444081 Replicon chromosome
Accession NZ_CP097262
Organism Salmonella enterica subsp. enterica strain B3-6

Toxin (Protein)


Gene name hokW Uniprot ID S1ELB5
Locus tag M3N94_RS11880 Protein ID WP_000813254.1
Coordinates 2443856..2444011 (-) Length 52 a.a.

Antitoxin (RNA)


Gene name sokW
Locus tag -
Coordinates 2444023..2444081 (+)

Genomic Context

--M3N94_RS11885M3N94_RS11890M3N94_RS11905M3N94_RS11910M3N94_RS11920M3N94_RS11845M3N94_RS11850M3N94_RS11855M3N94_RS11860M3N94_RS11865M3N94_RS11870M3N94_RS11875M3N94_RS11880M3N94_RS11895M3N94_RS11900M3N94_RS11915
Location: 2444023..2444081 (59 bp)
Type: Antitoxin
Protein ID: -
Location: 2444438..2445370 (933 bp)
Type: Others
Protein ID: WP_000556390.1
Location: 2445367..2445921 (555 bp)
Type: Others
Protein ID: WP_001033796.1
Location: 2446685..2447152 (468 bp)
Type: Others
Protein ID: WP_001227859.1
Location: 2447537..2447692 (156 bp)
Type: Others
Protein ID: WP_085981757.1
Location: 2448759..2448980 (222 bp)
Type: Others
Protein ID: WP_000560208.1
Location: 2438963..2439244 (282 bp)
Type: Others
Protein ID: WP_000445513.1
Location: 2439234..2439422 (189 bp)
Type: Others
Protein ID: WP_001688615.1
Location: 2439416..2439739 (324 bp)
Type: Others
Protein ID: Protein_2320
Location: 2441910..2442446 (537 bp)
Type: Others
Protein ID: WP_000640113.1
Location: 2442443..2442733 (291 bp)
Type: Others
Protein ID: WP_000774470.1
Location: 2442733..2443332 (600 bp)
Type: Others
Protein ID: WP_000940751.1
Location: 2443395..2443565 (171 bp)
Type: Others
Protein ID: WP_000734094.1
Location: 2443856..2444011 (156 bp)
Type: Toxin
Protein ID: WP_000813254.1
Location: 2446083..2446412 (330 bp)
Type: Others
Protein ID: WP_001676916.1
Location: 2446456..2446503 (48 bp)
Type: Others
Protein ID: Protein_2329
Location: 2447800..2448321 (522 bp)
Type: Others
Protein ID: WP_000004762.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
M3N94_RS118452438963..2439244-282WP_000445513.1phage holin family protein-
M3N94_RS118502439234..2439422-189WP_001688615.1putative holin-
M3N94_RS118552439416..2439739-324Protein_2320tellurite/colicin resistance protein-
M3N94_RS118602441910..2442446-537WP_000640113.1DUF1133 family protein-
M3N94_RS118652442443..2442733-291WP_000774470.1DUF1364 domain-containing protein-
M3N94_RS118702442733..2443332-600WP_000940751.1DUF1367 family protein-
M3N94_RS118752443395..2443565-171WP_000734094.1hypothetical protein-
M3N94_RS118802443856..2444011-156WP_000813254.1type I toxin-antitoxin system toxin HokDToxin
-2444023..2444081+59--Antitoxin
M3N94_RS118852444438..2445370+933WP_000556390.1hypothetical protein-
M3N94_RS118902445367..2445921+555WP_001033796.1hypothetical protein-
M3N94_RS118952446083..2446412-330WP_001676916.1DUF977 family protein-
M3N94_RS119002446456..2446503-48Protein_2329hypothetical protein-
M3N94_RS119052446685..2447152+468WP_001227859.1helix-turn-helix domain-containing protein-
M3N94_RS119102447537..2447692+156WP_085981757.1DUF1391 family protein-
M3N94_RS119152447800..2448321-522WP_000004762.1super-infection exclusion protein B-
M3N94_RS119202448759..2448980+222WP_000560208.1cell division protein FtsZ-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--2438421..245029211871


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5736.89 Da        Isoelectric Point: 6.1531

>T245077 WP_000813254.1 NZ_CP097262:c2444011-2443856 [Salmonella enterica subsp. enterica]
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEPEE

Download         Length: 156 bp

Antitoxin


Download         Length: 59 bp

>AT245077 NZ_CP097262:2444023-2444081 [Salmonella enterica subsp. enterica]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGCAAAGCATGAAATTGGCCTCA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4P7TMW0

Antitoxin

Download structure file

References