244931

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 111768..112283 Replicon chromosome
Accession NZ_CP097218
Organism Brachybacterium kimchii strain CBA3104

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag M4486_RS00540 Protein ID WP_249479062.1
Coordinates 112029..112283 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag M4486_RS00535 Protein ID WP_249479061.1
Coordinates 111768..112028 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4486_RS00510 (M4486_00510) 106892..107335 - 444 WP_249479056.1 DoxX family membrane protein -
M4486_RS00515 (M4486_00515) 107530..108633 + 1104 WP_249479057.1 redox-regulated ATPase YchF -
M4486_RS00520 (M4486_00520) 108630..110456 + 1827 WP_249479058.1 AAA family ATPase -
M4486_RS00525 (M4486_00525) 110577..110879 + 303 WP_249479059.1 HigA family addiction module antitoxin -
M4486_RS00530 (M4486_00530) 110894..111397 + 504 WP_249479060.1 AAA family ATPase -
M4486_RS00535 (M4486_00535) 111768..112028 + 261 WP_249479061.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M4486_RS00540 (M4486_00540) 112029..112283 + 255 WP_249479062.1 Txe/YoeB family addiction module toxin Toxin
M4486_RS00545 (M4486_00545) 112675..112977 + 303 WP_249479063.1 HigA family addiction module antitoxin -
M4486_RS00550 (M4486_00550) 112992..113516 + 525 WP_283257986.1 GNAT family protein -
M4486_RS00555 (M4486_00555) 113952..115117 + 1166 WP_249479065.1 IS3 family transposase -
M4486_RS19775 115537..115668 + 132 WP_264674020.1 hypothetical protein -
M4486_RS00560 (M4486_00560) 116044..116355 - 312 WP_228357725.1 antibiotic biosynthesis monooxygenase -
M4486_RS00565 (M4486_00565) 116363..116911 - 549 WP_062949524.1 type 1 glutamine amidotransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-67)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9955.32 Da        Isoelectric Point: 8.4536

>T244931 WP_249479062.1 NZ_CP097218:112029-112283 [Brachybacterium kimchii]
VRLVWDASAWEDYKHWQTTDRKVLKRINTLIDASLREPFAGIGKPEQLKYGAQGAWSRRITDEHRLVYLVVDDDLVILQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9654.78 Da        Isoelectric Point: 5.1532

>AT244931 WP_249479061.1 NZ_CP097218:111768-112028 [Brachybacterium kimchii]
MSVSASEARRTLFPLIERVNEDRDAVEIVSRKGNAVLMSADEYAAWQETAYLFRSPVNARRLLDAYDRARVGKTEVHGLD
RADEGA

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References