Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1687299..1687835 Replicon chromosome
Accession NZ_CP097160
Organism Gulosibacter sediminis strain ACHW.36C

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag M3M28_RS07775 Protein ID WP_249385932.1
Coordinates 1687608..1687835 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag M3M28_RS07770 Protein ID WP_249385931.1
Coordinates 1687299..1687595 (-) Length 99 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M28_RS07755 (M3M28_07755) 1682409..1685339 - 2931 WP_249385928.1 helicase-related protein -
M3M28_RS07760 (M3M28_07760) 1685478..1686335 + 858 WP_249385929.1 hypothetical protein -
M3M28_RS07765 (M3M28_07765) 1686385..1687281 - 897 WP_249385930.1 hypothetical protein -
M3M28_RS07770 (M3M28_07770) 1687299..1687595 - 297 WP_249385931.1 HigA family addiction module antitoxin Antitoxin
M3M28_RS07775 (M3M28_07775) 1687608..1687835 - 228 WP_249385932.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M3M28_RS07780 (M3M28_07780) 1688598..1689413 + 816 WP_249385933.1 hypothetical protein -
M3M28_RS07785 (M3M28_07785) 1689394..1690686 - 1293 WP_249385934.1 amidase -
M3M28_RS07790 (M3M28_07790) 1690782..1692167 - 1386 WP_249385935.1 lipase maturation factor family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-74)

Antitoxin

(18-65)


Sequences


Toxin        


Download         Length: 76 a.a.        Molecular weight: 8306.47 Da        Isoelectric Point: 9.7162

>T244828 WP_249385932.1 NZ_CP097160:c1687835-1687608 [Gulosibacter sediminis]
VASLRPDLQRAAQKKLRLLNGASTLGSLRVRPGNRLEKLNGDRAGQYSIRVNSQYRICFVCVDGGAEDVEITDYL

Download         Length: 228 bp


Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11090.72 Da        Isoelectric Point: 7.2047

>AT244828 WP_249385931.1 NZ_CP097160:c1687595-1687299 [Gulosibacter sediminis]
MAKAHAPITPGEILRTEFLEPMGISQYRLAKATGLSQTRISEIIRGKRSITIETALRLSKALGVDDRFWINLQARYDLEV
ERDRHGDEIDRIESLIAG

Download         Length: 297 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References