Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 1094953..1095475 Replicon chromosome
Accession NZ_CP097119
Organism Fructilactobacillus cliffordii strain KI4_B1

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag M3M40_RS05655 Protein ID WP_252766489.1
Coordinates 1094953..1095231 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag M3M40_RS05660 Protein ID WP_252766490.1
Coordinates 1095224..1095475 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M40_RS05625 (M3M40_05625) 1090068..1090268 + 201 WP_252766483.1 helix-turn-helix transcriptional regulator -
M3M40_RS05630 (M3M40_05630) 1090359..1090769 + 411 WP_252766484.1 ImmA/IrrE family metallo-endopeptidase -
M3M40_RS05635 (M3M40_05635) 1091030..1091392 - 363 WP_252766485.1 hypothetical protein -
M3M40_RS05640 (M3M40_05640) 1091586..1093736 - 2151 WP_252766486.1 DUF1906 domain-containing protein -
M3M40_RS05645 (M3M40_05645) 1093987..1094304 + 318 WP_252766487.1 helix-turn-helix transcriptional regulator -
M3M40_RS05650 (M3M40_05650) 1094285..1094695 + 411 WP_252766488.1 ImmA/IrrE family metallo-endopeptidase -
M3M40_RS05655 (M3M40_05655) 1094953..1095231 - 279 WP_252766489.1 type II toxin-antitoxin system YafQ family toxin Toxin
M3M40_RS05660 (M3M40_05660) 1095224..1095475 - 252 WP_252766490.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M3M40_RS05665 (M3M40_05665) 1096305..1097036 - 732 WP_252766491.1 LysM domain-containing protein -
M3M40_RS05670 (M3M40_05670) 1097308..1098999 - 1692 WP_252766492.1 alpha-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1088511..1104287 15776


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-67)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11401.97 Da        Isoelectric Point: 8.3471

>T244801 WP_252766489.1 NZ_CP097119:c1095231-1094953 [Fructilactobacillus cliffordii]
MTKQYKPAFENQFKKHYKQMLKQPKYNKNQFNEIYYLLINDEEIPAKFNDHNLINRKPERELHIKPDWLLIYRYDGDYIK
FIDTGSHSDLFE

Download         Length: 279 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9591.75 Da        Isoelectric Point: 5.8150

>AT244801 WP_252766490.1 NZ_CP097119:c1095475-1095224 [Fructilactobacillus cliffordii]
MKTNTAQIHFRTSTLNKDEFEKVLKENGLTAPEAFRIFMKQTINNNGLPFEVNQPNKRLKTAISSDDYVKFDNAQEGLDW
LND

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References