Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 6284474..6285146 Replicon chromosome
Accession NZ_CP097108
Organism Pseudomonas bijieensis strain SP1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag M3M50_RS27930 Protein ID WP_109754987.1
Coordinates 6284781..6285146 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag M3M50_RS27925 Protein ID WP_109754986.1
Coordinates 6284474..6284788 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M50_RS27915 (M3M50_27915) 6281521..6283953 + 2433 WP_249015642.1 DUF308 domain-containing protein -
M3M50_RS27920 (M3M50_27920) 6283990..6284451 + 462 WP_018607342.1 Lrp/AsnC family transcriptional regulator -
M3M50_RS27925 (M3M50_27925) 6284474..6284788 - 315 WP_109754986.1 XRE family transcriptional regulator Antitoxin
M3M50_RS27930 (M3M50_27930) 6284781..6285146 - 366 WP_109754987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M3M50_RS27935 (M3M50_27935) 6285507..6287189 + 1683 WP_249015643.1 NAD(P)/FAD-dependent oxidoreductase -
M3M50_RS27940 (M3M50_27940) 6287202..6287996 + 795 WP_109754989.1 carbon-nitrogen hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(16-86)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14013.68 Da        Isoelectric Point: 4.9669

>T244799 WP_109754987.1 NZ_CP097108:c6285146-6284781 [Pseudomonas bijieensis]
MKWDVEYTDEFEMWWSCLSETEQDSVQASVMLLGDAGPHLGFPHTSDIKGSRHGNLRELRVQHAGRPYRVLYAFDPRRCA
ILLIGGDKTGQDRWYQECVPLAERLYDEHLEALKREGFDNG

Download         Length: 366 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12002.75 Da        Isoelectric Point: 9.9863

>AT244799 WP_109754986.1 NZ_CP097108:c6284788-6284474 [Pseudomonas bijieensis]
MAKKFSDLIARRSPDSRARAETLYQKLRAEMPLHELRQAQELSQDALAKTLHINQAAVSKMERRTDMYISTLRNYIRAMG
GELEIIATFPEGQVRIENFAHQTQ

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References