Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5712531..5713186 Replicon chromosome
Accession NZ_CP097108
Organism Pseudomonas bijieensis strain SP1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag M3M50_RS25235 Protein ID WP_109754833.1
Coordinates 5712842..5713186 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag M3M50_RS25230 Protein ID WP_003205391.1
Coordinates 5712531..5712845 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M50_RS25210 (M3M50_25210) 5708440..5709357 + 918 WP_249015535.1 LysR family transcriptional regulator -
M3M50_RS25215 (M3M50_25215) 5709601..5710614 + 1014 WP_109754830.1 sensor domain-containing diguanylate cyclase -
M3M50_RS25220 (M3M50_25220) 5710707..5711450 + 744 WP_249015536.1 DUF72 domain-containing protein -
M3M50_RS25225 (M3M50_25225) 5711589..5712293 + 705 WP_109754832.1 hypothetical protein -
M3M50_RS25230 (M3M50_25230) 5712531..5712845 - 315 WP_003205391.1 helix-turn-helix domain-containing protein Antitoxin
M3M50_RS25235 (M3M50_25235) 5712842..5713186 - 345 WP_109754833.1 toxin Toxin
M3M50_RS25240 (M3M50_25240) 5713326..5714213 - 888 WP_109754834.1 heme o synthase -
M3M50_RS25245 (M3M50_25245) 5714225..5714560 - 336 WP_025211927.1 cytochrome o ubiquinol oxidase subunit IV -
M3M50_RS25250 (M3M50_25250) 5714561..5715187 - 627 WP_109754835.1 cytochrome o ubiquinol oxidase subunit III -
M3M50_RS25255 (M3M50_25255) 5715191..5717221 - 2031 WP_109754836.1 cytochrome o ubiquinol oxidase subunit I -
M3M50_RS25260 (M3M50_25260) 5717225..5718172 - 948 WP_003205397.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(47-87)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13680.71 Da        Isoelectric Point: 9.2887

>T244798 WP_109754833.1 NZ_CP097108:c5713186-5712842 [Pseudomonas bijieensis]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYMLEHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELVNLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11771.76 Da        Isoelectric Point: 9.8409

>AT244798 WP_003205391.1 NZ_CP097108:c5712845-5712531 [Pseudomonas bijieensis]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References