Detailed information of TA system TA244683

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2662204..2662487
• Replicon: chromosome
• Accession: NZ_CP097066
• Organism: Enterococcus faecalis strain AT49a

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2922_RS12655
• Protein ID: WP_002411240.1
• Coordinates: 2662204..2662353 (+)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2662286..2662487 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2922_RS12635 (2657422)	2657422..2657637	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
M2922_RS12640 (2657776)	2657776..2658768	+	993	WP_002378862.1	biotin--[acetyl-CoA-carboxylase] ligase	-
M2922_RS12645 (2658935)	2658935..2659573	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
M2922_RS12650 (2660259)	2660259..2661875	+	1617	WP_174114069.1	phosphatase PAP2/LCP family protein	-
M2922_RS12655 (2662204)	2662204..2662353	+	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	Toxin
- (2662327)	2662327..2662473	-	147	NuclAT_12	-	-
- (2662286)	2662286..2662487	-	202	NuclAT_8	-	Antitoxin
M2922_RS12660 (2662584)	2662584..2662727	+	144	WP_016619108.1	putative holin-like toxin	-
- (2662871)	2662871..2662920	+	50	NuclAT_16	-	-
- (2662659)	2662659..2662921	-	263	NuclAT_11	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (16-49)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5738.05 Da
• Isoelectric Point: 11.3858

>T244683 WP_002411240.1 NZ_CP097066:2662204-2662353 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 150 bp

Antitoxin

Nucleotide

• Length: 202 bp

>AT244683 NZ_CP097066:c2662487-2662286 [Enterococcus faecalis]
GTTTTTTTAGGTAATTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTA
AGACGGTGACCTTTTTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCA
ATTTCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin