Detailed information of TA system TA244639

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2653449..2653709
• Replicon: chromosome
• Accession: NZ_CP097059
• Organism: Enterococcus faecalis strain AT04

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2902_RS12750
• Protein ID: WP_156194032.1
• Coordinates: 2653566..2653709 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2653449..2653633 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2902_RS12735	2649010..2649723	-	714	WP_002354877.1	trehalose operon repressor	-
M2902_RS12740	2649985..2652729	+	2745	WP_002404790.1	glycosyl hydrolase family 65 protein	-
M2902_RS12745	2652744..2653394	+	651	WP_002359015.1	beta-phosphoglucomutase	-
-	2653449..2653633	+	185	-	-	Antitoxin
M2902_RS12750	2653566..2653709	-	144	WP_156194032.1	type I toxin-antitoxin system toxin PepG1	Toxin
M2902_RS12755	2653940..2654911	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
M2902_RS12760	2655086..2655523	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
M2902_RS12765	2655656..2656210	-	555	WP_002359011.1	Maf family protein	-
M2902_RS12770	2656235..2658367	-	2133	WP_085366626.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5327.50 Da
• Isoelectric Point: 10.8331

>T244639 WP_156194032.1 NZ_CP097059:c2653709-2653566 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTISLIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT244639 NZ_CP097059:2653449-2653633 [Enterococcus faecalis]
TGCTAGAATGTAGATGAAAAGAGAGAGATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTGAGACGGTGACCAATTGT
ATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGAAATGGTAAACATACCAA

Structures

Antitoxin