Detailed information of TA system TA244624

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 2735596..2735865
• Replicon: chromosome
• Accession: NZ_CP097056
• Organism: Enterococcus faecalis strain AT09

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2903_RS13170
• Protein ID: WP_002411240.1
• Coordinates: 2735596..2735745 (+)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2735719..2735865 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2903_RS13150 (2730814)	2730814..2731029	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
M2903_RS13155 (2731168)	2731168..2732160	+	993	WP_002378862.1	biotin--[acetyl-CoA-carboxylase] ligase	-
M2903_RS13160 (2732327)	2732327..2732965	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
M2903_RS13165 (2733651)	2733651..2735267	+	1617	WP_174114069.1	phosphatase PAP2/LCP family protein	-
M2903_RS13170 (2735596)	2735596..2735745	+	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	Toxin
- (2735719)	2735719..2735865	-	147	NuclAT_12	-	Antitoxin
- (2735678)	2735678..2735879	-	202	NuclAT_8	-	-
M2903_RS13175 (2735976)	2735976..2736119	+	144	WP_016619108.1	putative holin-like toxin	-
- (2736263)	2736263..2736312	+	50	NuclAT_16	-	-
- (2736051)	2736051..2736313	-	263	NuclAT_11	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (16-49)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5738.05 Da
• Isoelectric Point: 11.3858

>T244624 WP_002411240.1 NZ_CP097056:2735596-2735745 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 150 bp

Antitoxin

Nucleotide

• Length: 147 bp

>AT244624 NZ_CP097056:c2735865-2735719 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCTTT
TTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAA

Structures

Antitoxin