Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 519529..519761 Replicon chromosome
Accession NZ_CP097056
Organism Enterococcus faecalis strain AT09

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag M2903_RS02570 Protein ID WP_002355568.1
Coordinates 519529..519645 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 519556..519761 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2903_RS02560 (514967) 514967..517225 + 2259 WP_002364805.1 DNA helicase PcrA -
M2903_RS02565 (517351) 517351..519381 + 2031 WP_002364804.1 NAD-dependent DNA ligase LigA -
M2903_RS02570 (519529) 519529..519645 + 117 WP_002355568.1 putative holin-like toxin Toxin
- (519556) 519556..519761 - 206 NuclAT_3 - Antitoxin
M2903_RS02575 (519963) 519963..520268 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
M2903_RS02580 (520268) 520268..521737 + 1470 WP_002358701.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
M2903_RS02585 (521737) 521737..523167 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
M2903_RS02590 (523186) 523186..524274 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T244605 WP_002355568.1 NZ_CP097056:519529-519645 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT244605 NZ_CP097056:c519761-519556 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References