244599

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2752520..2752856 Replicon chromosome
Accession NZ_CP097048
Organism Enterococcus faecalis strain AT22

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag M2906_RS13235 Protein ID WP_002396786.1
Coordinates 2752520..2752663 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2752807..2752856 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2906_RS13215 (2747798) 2747798..2748013 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
M2906_RS13220 (2748152) 2748152..2749144 + 993 WP_002394775.1 biotin--[acetyl-CoA-carboxylase] ligase -
M2906_RS13225 (2749311) 2749311..2749949 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
M2906_RS13230 (2750634) 2750634..2752250 + 1617 WP_010710855.1 phosphatase PAP2/LCP family protein -
- (2752334) 2752334..2752409 - 76 NuclAT_7 - -
- (2752307) 2752307..2752423 - 117 NuclAT_10 - -
M2906_RS13235 (2752520) 2752520..2752663 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2752807) 2752807..2752856 + 50 NuclAT_8 - Antitoxin
- (2752595) 2752595..2752857 - 263 NuclAT_5 - -
M2906_RS13240 (2752858) 2752858..2757549 - 4692 WP_010710853.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T244599 WP_002396786.1 NZ_CP097048:2752520-2752663 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 50 bp

>AT244599 NZ_CP097048:2752807-2752856 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References