244587

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 467247..467491 Replicon chromosome
Accession NZ_CP097048
Organism Enterococcus faecalis strain AT22

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag M2906_RS02315 Protein ID WP_225582204.1
Coordinates 467247..467375 (+) Length 43 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 467286..467491 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2906_RS02305 (462697) 462697..464955 + 2259 WP_010710797.1 DNA helicase PcrA -
M2906_RS02310 (465081) 465081..467111 + 2031 WP_010710796.1 NAD-dependent DNA ligase LigA -
M2906_RS02315 (467247) 467247..467375 + 129 WP_225582204.1 putative holin-like toxin Toxin
- (467286) 467286..467491 - 206 NuclAT_2 - Antitoxin
M2906_RS02320 (467693) 467693..467998 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
M2906_RS02325 (467998) 467998..469467 + 1470 WP_002368026.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
M2906_RS02330 (469467) 469467..470897 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
M2906_RS02335 (470916) 470916..472004 + 1089 WP_002396964.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(7-39)


Sequences

Toxin        


Download         Length: 43 a.a.        Molecular weight: 4453.43 Da        Isoelectric Point: 8.9940

>T244587 WP_225582204.1 NZ_CP097048:467247-467375 [Enterococcus faecalis]
MKGAMFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 129 bp

Antitoxin


Download         Length: 206 bp

>AT244587 NZ_CP097048:c467491-467286 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References