244558

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 486875..487107 Replicon chromosome
Accession NZ_CP097046
Organism Enterococcus faecalis strain AT29

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag M2907_RS02375 Protein ID WP_002355568.1
Coordinates 486875..486991 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 486902..487107 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2907_RS02365 (482313) 482313..484571 + 2259 WP_002364805.1 DNA helicase PcrA -
M2907_RS02370 (484697) 484697..486727 + 2031 WP_002364804.1 NAD-dependent DNA ligase LigA -
M2907_RS02375 (486875) 486875..486991 + 117 WP_002355568.1 putative holin-like toxin Toxin
- (486902) 486902..487107 - 206 NuclAT_3 - Antitoxin
M2907_RS02380 (487309) 487309..487614 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
M2907_RS02385 (487614) 487614..489083 + 1470 WP_002358701.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
M2907_RS02390 (489083) 489083..490513 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
M2907_RS02395 (490532) 490532..491620 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T244558 WP_002355568.1 NZ_CP097046:486875-486991 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT244558 NZ_CP097046:c487107-486902 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References