244555

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2662420..2662755 Replicon chromosome
Accession NZ_CP097042
Organism Enterococcus faecalis strain AT34

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag M2910_RS12560 Protein ID WP_002415596.1
Coordinates 2662420..2662563 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2662705..2662755 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2910_RS12540 (2657488) 2657488..2657703 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
M2910_RS12545 (2657842) 2657842..2658834 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
M2910_RS12550 (2659138) 2659138..2659776 - 639 WP_002375448.1 lytic polysaccharide monooxygenase -
M2910_RS12555 (2660463) 2660463..2662079 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
M2910_RS12560 (2662420) 2662420..2662563 + 144 WP_002415596.1 type I toxin-antitoxin system toxin PepG1 Toxin
- (2662496) 2662496..2662754 - 259 NuclAT_3 - -
- (2662705) 2662705..2662755 + 51 NuclAT_13 - Antitoxin
M2910_RS12565 (2662756) 2662756..2666523 - 3768 WP_104807327.1 WxL domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(14-47)


Sequences


Toxin        


Download         Length: 48 a.a.        Molecular weight: 5314.46 Da        Isoelectric Point: 10.6323

>T244555 WP_002415596.1 NZ_CP097042:2662420-2662563 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 144 bp


Antitoxin


Download         Length: 51 bp

>AT244555 NZ_CP097042:2662705-2662755 [Enterococcus faecalis]
AATAAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References