Detailed information of TA system TA244553

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2662420..2662754
• Replicon: chromosome
• Accession: NZ_CP097042
• Organism: Enterococcus faecalis strain AT34

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2910_RS12560
• Protein ID: WP_002415596.1
• Coordinates: 2662420..2662563 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2662496..2662754 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2910_RS12540 (2657488)	2657488..2657703	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
M2910_RS12545 (2657842)	2657842..2658834	+	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
M2910_RS12550 (2659138)	2659138..2659776	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
M2910_RS12555 (2660463)	2660463..2662079	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
M2910_RS12560 (2662420)	2662420..2662563	+	144	WP_002415596.1	type I toxin-antitoxin system toxin PepG1	Toxin
- (2662496)	2662496..2662754	-	259	NuclAT_3	-	Antitoxin
- (2662705)	2662705..2662755	+	51	NuclAT_13	-	-
M2910_RS12565 (2662756)	2662756..2666523	-	3768	WP_104807327.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5314.46 Da
• Isoelectric Point: 10.6323

>T244553 WP_002415596.1 NZ_CP097042:2662420-2662563 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 259 bp

>AT244553 NZ_CP097042:c2662754-2662496 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAA
TGATAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTACTT
AAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAA
GCAATGGTAAACATACCAA

Structures

Antitoxin