Detailed information of TA system TA244550

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2583975..2584246
• Replicon: chromosome
• Accession: NZ_CP097042
• Organism: Enterococcus faecalis strain AT34

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2910_RS12215
• Protein ID: WP_002375510.1
• Coordinates: 2584094..2584246 (-)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2583975..2584161 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2910_RS12200 (2579942)	2579942..2582686	+	2745	WP_104807179.1	glycosyl hydrolase family 65 protein	-
M2910_RS12205 (2582701)	2582701..2583351	+	651	WP_002375514.1	beta-phosphoglucomutase	-
- (2583420)	2583420..2583552	+	133	NuclAT_12	-	-
- (2583599)	2583599..2583786	+	188	NuclAT_4	-	-
M2910_RS12210 (2583719)	2583719..2583823	-	105	WP_023894767.1	putative holin-like toxin	-
- (2583975)	2583975..2584120	+	146	NuclAT_11	-	-
- (2583975)	2583975..2584161	+	187	NuclAT_5	-	Antitoxin
M2910_RS12215 (2584094)	2584094..2584246	-	153	WP_002375510.1	type I toxin-antitoxin system toxin PepG1	Toxin
M2910_RS12220 (2584471)	2584471..2585442	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
M2910_RS12225 (2585617)	2585617..2586054	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
M2910_RS12230 (2586187)	2586187..2586741	-	555	WP_002354869.1	Maf family protein	-
M2910_RS12235 (2586766)	2586766..2588898	-	2133	WP_248869279.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (17-50)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5637.90 Da
• Isoelectric Point: 11.0942

>T244550 WP_002375510.1 NZ_CP097042:c2584246-2584094 [Enterococcus faecalis]
VVRMSALPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 153 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT244550 NZ_CP097042:2583975-2584161 [Enterococcus faecalis]
TGTGCTATAATGAAAATGAAAAGAGAGATATGAGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTTTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin