244535

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2718213..2718550 Replicon chromosome
Accession NZ_CP097038
Organism Enterococcus faecalis strain AT39

Toxin (Protein)


Gene name txpA Uniprot ID E2Z0W4
Locus tag M2911_RS12910 Protein ID WP_002381035.1
Coordinates 2718213..2718356 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2718288..2718550 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2911_RS12895 2713929..2714561 - 633 WP_002358972.1 RloB family protein -
M2911_RS12900 2714570..2715865 - 1296 WP_248882009.1 ATP-binding protein -
M2911_RS12905 2716327..2717943 + 1617 WP_002406969.1 phosphatase PAP2/LCP family protein -
M2911_RS12910 2718213..2718356 + 144 WP_002381035.1 putative holin-like toxin Toxin
- 2718288..2718550 - 263 - - Antitoxin
M2911_RS12915 2718551..2721550 - 3000 WP_033786695.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5202.20 Da        Isoelectric Point: 10.0041

>T244535 WP_002381035.1 NZ_CP097038:2718213-2718356 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKENNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT244535 NZ_CP097038:c2718550-2718288 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGACAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTTTTCTTTTACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2Z6BWH2

Antitoxin

Download structure file

References