Detailed information of TA system TA244530

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2568428..2568908
• Replicon: chromosome
• Accession: NZ_CP097038
• Organism: Enterococcus faecalis strain AT39

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2911_RS12235
• Protein ID: WP_224800345.1
• Coordinates: 2568428..2568529 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2568703..2568908 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2911_RS12210	2563957..2564910	-	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-
M2911_RS12215	2564949..2565704	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
M2911_RS12220	2565701..2566666	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
M2911_RS12225	2566663..2567610	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
M2911_RS12230	2567795..2568247	+	453	WP_002378959.1	YueI family protein	-
M2911_RS12235	2568428..2568529	-	102	WP_224800345.1	putative holin-like toxin	Toxin
-	2568703..2568908	+	206	-	-	Antitoxin
M2911_RS12240	2569432..2571702	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
M2911_RS12245	2571873..2572379	+	507	WP_010710886.1	cysteine hydrolase family protein	-
M2911_RS12250	2572569..2573465	+	897	WP_002368434.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3594.37 Da
• Isoelectric Point: 6.0656

>T244530 WP_224800345.1 NZ_CP097038:c2568529-2568428 [Enterococcus faecalis]
MSIEAALELMISFATLVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 206 bp

>AT244530 NZ_CP097038:2568703-2568908 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTATTT
TTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin