Detailed information of TA system TA244524

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 300376..300570
• Replicon: chromosome
• Accession: NZ_CP097038
• Organism: Enterococcus faecalis strain AT39

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: M2911_RS01505
• Protein ID: WP_162781186.1
• Coordinates: 300475..300570 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	300376..300440 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2911_RS01490	295994..297736	+	1743	WP_002397018.1	PTS transporter subunit EIIC	-
M2911_RS01495	297727..299760	+	2034	WP_002361171.1	PRD domain-containing protein	-
M2911_RS01500	299771..300205	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	300376..300440	+	65	-	-	Antitoxin
M2911_RS01505	300475..300570	-	96	WP_162781186.1	type I toxin-antitoxin system Fst family toxin	Toxin
M2911_RS01510	300816..302588	+	1773	WP_113847474.1	PTS mannitol-specific transporter subunit IIBC	-
M2911_RS01515	302603..303040	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
M2911_RS01520	303055..304209	+	1155	WP_002395429.1	mannitol-1-phosphate 5-dehydrogenase	-
M2911_RS01525	304276..305391	-	1116	WP_033785759.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3658.53 Da
• Isoelectric Point: 8.6635

>T244524 WP_162781186.1 NZ_CP097038:c300570-300475 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNKE

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT244524 NZ_CP097038:300376-300440 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin